The health of individuals living in developed and developing countries remain at risk due to the current global environmental pollution scenario, which is alarmingly leading to the rise in infectious and chronic diseases. Also, the health of living communities worldwide is seriously threatened by the rise in antibiotic-resistant strains of bacteria. Because of their adverse impacts on patients, the medications now used in the modern medical system aren't able to treat diseases, especially those that are resistant, in a way that is both economical and long-lasting. This has made it necessary to keep doing research in order to adequately address the health issues. Hence, medicinal plants are an indisputable asset in the treatment of a wide range of ailments because of its efficiency, low side effect rate and affordability. Due to their ability to alter the body's immune system and increase resistance to complicated illnesses, medicinal herbs offer a sustainable and environmentally friendly approach to managing humanity's health issues. The Ayurvedic medical system makes considerable use of Cassia fistula Linn. as one of its therapeutic herbs to treat a wide range of diseases. It is widely practiced in India's traditional medical system. The tree, which goes by the name "Yellow Shower," is a medium-sized deciduous tree with elongated, rod-shaped fruits that are packed with pulp and vivid yellow blooms. An updated version of its botanical description, traditional uses, phytochemical constituent and pharmacological properties-such as antidiabetic, antioxidant, hepatoprotective, antifertility, hypolipidemic, immunomodulatory, anticancer, laxative, anti-inflammatory, antipyretic, antimicrobial, antifungal and antiparasitic effects-are provided in this review. Reviews of pharmacological properties of medicinal plants will yield useful information; hence, Cassia fistula Linn. may yield significant bioactive natural product discoveries that will aid in the development of new pharmaceutical products.