Pharmacognosy Research
Journal Impact
(As per Journal Citation Reports 2026)
Category: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery and Pharmaceutical Science
Sources: Journal Citation Reports from Clarivate, 2026 release.
Pharmacognosy Research
Volume 19, Issue 1 • 2027
Shenmai Injection Attenuates Pressure Overload-Induced Cardiac Hypertrophy by Modulating HRAS
Background/Objectives: Pressure overload-induced cardiac hypertrophy is a critical pathological precursor in the development of heart failure. Shenmai Injection (SMI) is widely used to treat cardiovascular diseases. However, its anti-hypertrophic effects and underlying molecular mechanisms remain insufficiently elucida


Modulation of KEAP1/NRF2-Regulated Anticancer Chemopreventive Signalling Pathways by Anacardic Acid in MCF7-ARE Human Breast Cancer Cells
Background: Breast cancer is the most diagnosed cancer worldwide, with an escalating burden over the past decades. Anacardic Acid (AA), a phenolic lipid extracted from cashew nutshell, displays diverse therapeutic properties including anti-tumor effects. However, the molecular mechanisms underlying the anticancer effec

Taxonomic Characterization and Ethnobotanical Insights of Bergenia ciliata Used by Hakeems in the Kashmir Himalaya
Background: The Kashmir Himalaya is known for its rich diversity of medicinal plants that support traditional healthcare systems, where indigenous knowledge plays a vital role in disease management. Among these, Bergenia ciliata is widely recognized for its therapeutic potential; however, comprehensive studies integrat

Pharmacognostical Standardization of Leaf and Stem Bark of Elaeodendron glaucum (Rottb.) Pers.- An Important Ethno-Medicinal Plant
Background: Elaeodendron glaucum (Rottb.) Pers. is an essential ethnomedicinal plant belonging to Celastraceae used in the treatment of various ailments like antidotes for snake bites, dog bites, wounds and cracks, dysuria, swellings, burning sensations, hyperacidity, dysentery, headaches, fever, etc. Aim: The Present

Development and Quality Assessment of Poshakriti: A Gluten-Free, Multipurpose, Multigrain, Nutritional Flour
Background: Growing awareness of the health-nutrition interface and demand for convenient yet wholesome foods is rising. Traditional Indian diets, influenced by Ayurvedic principles, emphasize balanced combinations of cereals, pulses, and spices. Objectives: Building on this knowledge, a novel gluten-free, millet-rich

Anticancer Effects of Schinus molle-Synthesized Iron Nanoparticles in Human Hela Cervical Cancer Cells
Objectives: Green development of iron nanoparticles by plant derived extracts has collected important scientific attention due to their eco-friendly fabrication, cost-effectiveness, and enhanced biological activities. Materials and Methods: The current research was assumed to evaluate the anticancer efficacy of Iron N

Daidzein Attenuates Allergic Asthma via NF-κB1 Downregulation and Cytokine Modulation: A Comprehensive Preclinical Evaluation
Background: Bronchial Asthma (BA) is a chronic inflammatory airway disorder strongly associated with immune system dysregulation. Daidzein, a natural isoflavone found in soy, exhibits well-documented anti-inflammatory and immunomodulatory activities, including inhibition of dendritic cell maturation and regulation of e

Comparative Structural and Biophysical Profiling of Dengue Virus NS5 Methyltransferase Identifies DENV-4 as a Prioritized Antiviral Target
Background: The NS5 Methyltransferase (MTase) domain is essential for the capping and replication of dengue virus RNA and for the virus's evasion of the host immune response, making it a promising antiviral target. Purpose: To assess the structural and biophysical characteristics of the NS5 MTase across the four Dengu

Elucidating the role of Shatapushpa (Anethum graveolens L.) in Rheumatoid Arthritis through In vitro and In silico Analysis
Introduction: Day by day the prevalence of the diseases are increasing throughout the globe. One such disease that is having increase in incidence is Rheumatoid Arthritis (RA). With the rise in the occurrence there is need of newer drugs with safety and efficacy. Shatapushpa (Anethum graveolens L.) in Ayurveda is used

Isolation and Characterization of Saponins from Asparagus racemosus: A HPTLC and LC-MS Study
Background: Shatavari or Asparagus racemosus Wild. Family Liliaceae is an important therapeutic herb in the health care system. It contains a sapogenin content which is a precursor of many pharmacologically active steroids. This plant is used to induce menstruation and as a cosmetic tonic. Objectives: The objective of

Phytochemical and Pharmacological Potential of Pithecellobium dulce: A Review
Pithecellobium dulce (Roxb.) Benth is a medicinal plant that is commonly used in traditional medicine and its phytochemical profile has shown to contain numerous bioactive compounds which are characterized by the presence of high concentration of flavonoids (42-57 mg QE/g), phenolics (30-75 mg GAE/g), tannins, alkaloid

Green-Synthesized Tribulus terrestris-Mediated CuO Nanoparticle-Loaded CS/PVA Hydrogels: A Multifunctional Platform for Cancer Therapy and Antidiabetic Applications
Objectives: In this work, we report on the preparation of CuO nanoparticles using extract from Tribulus terrestris as a natural reducing and stabilizing agent, followed by the loading of the nanoparticles into the Chitosan/Poly (vinyl alcohol) (CS/PVA) hydrogel in order to design a multifunctional system for treating c

Deep Eutectic Solvent as Green Alternative Solvents for Polygodial Extraction with Validated HPLC-UV Analysis and Evaluation of their Bioactivities
Introduction: Akway (Tasmannia piperita), a native Papua plant is known for its benefits as stamina enhancer, antimicrobial, and antioxidant agents, which can be associated to polygodial, its marker compound. Green alternative solvents for polygodial extraction are required. Objectives: In this study, an HPLC-UV metho
