Pharmacognosy Research
Journal Impact
(As per Journal Citation Reports 2026)
Category: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery and Pharmaceutical Science
Sources: Journal Citation Reports from Clarivate, 2026 release.
Pharmacognosy Research
Volume 19, Issue 1 • 2027
Comparative Structural and Biophysical Profiling of Dengue Virus NS5 Methyltransferase Identifies DENV-4 as a Prioritized Antiviral Target
Background: The NS5 Methyltransferase (MTase) domain is essential for the capping and replication of dengue virus RNA and for the virus's evasion of the host immune response, making it a promising antiviral target. Purpose: To assess the structural and biophysical characteristics of the NS5 MTase across the four Dengu


High Performance Thin Layer Chromatography (HPTLC) Methods for Simultaneous Estimation and Quantification of Vasicine, Gallic acid, Piperine and Pterostilbene from Two Ayurvedic Formulations and Herbal Extracts
Background: High Performance Thin Layer Chromatography (HPTLC) is an advanced analytical technique used for the identification and quantification of marker compounds in Ayurvedic formulations. Aims and Objectives: The purpose of this study is to create and validate an HPTLC method for the simultaneous estimation and q

Deep Eutectic Solvent as Green Alternative Solvents for Polygodial Extraction with Validated HPLC-UV Analysis and Evaluation of their Bioactivities
Introduction: Akway (Tasmannia piperita), a native Papua plant is known for its benefits as stamina enhancer, antimicrobial, and antioxidant agents, which can be associated to polygodial, its marker compound. Green alternative solvents for polygodial extraction are required. Objectives: In this study, an HPLC-UV metho

GC-MS Phytochemical Profiling of Kaidarya Siddha Narikela Taila: Mechanistic Insights into Khalitya (Non-Specific Hairfall) Management
Background: Non-Specific Hairfall (NSHF), classified as Khalitya in Ayurveda (NAMC FA-3, ICD-11 TM2), has a significant global burden. Kaidarya siddha Narikela Taila (KNT) is a formulation prepared with Narikela Taila (Cocos nucifera) and Kaidarya kashaya (decoction of Murraya koenigii), widely utilised in the manageme

Camellia sinensis Extract Mediated Synthesis of Fe3O4 Magnetic Nanoparticles for pH-Responsive Targeted Breast Cancer Therapy
Objectives: One challenge in treating breast cancer is that there are not enough drug delivery systems that can both target tumors specifically and have their own pharmacological effects. Materials and Methods: This study prepared Fe3O4 Magnetic Nanoparticles (Cs-MNPs) from a one-pot aqueous reaction using Camellia si

Shenmai Injection Attenuates Pressure Overload-Induced Cardiac Hypertrophy by Modulating HRAS
Background/Objectives: Pressure overload-induced cardiac hypertrophy is a critical pathological precursor in the development of heart failure. Shenmai Injection (SMI) is widely used to treat cardiovascular diseases. However, its anti-hypertrophic effects and underlying molecular mechanisms remain insufficiently elucida

Phytochemical and Pharmacological Potential of Pithecellobium dulce: A Review
Pithecellobium dulce (Roxb.) Benth is a medicinal plant that is commonly used in traditional medicine and its phytochemical profile has shown to contain numerous bioactive compounds which are characterized by the presence of high concentration of flavonoids (42-57 mg QE/g), phenolics (30-75 mg GAE/g), tannins, alkaloid

Isolation and Characterization of Saponins from Asparagus racemosus: A HPTLC and LC-MS Study
Background: Shatavari or Asparagus racemosus Wild. Family Liliaceae is an important therapeutic herb in the health care system. It contains a sapogenin content which is a precursor of many pharmacologically active steroids. This plant is used to induce menstruation and as a cosmetic tonic. Objectives: The objective of

Comparative Analysis of Multi-Solvent Tinospora cordifolia Fresh and Dry Leaf Extract Using Advanced Analytical Approaches
Background: Tinospora cordifolia is used worldwide for its medicinal properties, but its bioactive phytoconstituents have been less explored. Objectives: The fresh and dry leaf extracts of Tinospora cordifolia, a traditional medicinal plant, were comparatively analysed for their phytochemical content and therapeutic p

Targeted Neurotherapeutics: A Review of Bacopa monnieri Delivery Strategies for Neurodegeneration
Neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Autism lead to Central Nervous System (CNS) degeneration, impairing both cognitive and motor functions. With the rising prevalence of these illnesses-closely linked to age and lifestyle factors-effective therapeutic strategies that can cr

Comparative GC-MS Profiling of n-Hexane Extracts from the Heartwood and Small Branches of Pterocarpus santalinus Linn.f.
Background: Pterocarpus santalinus Linn.f. (Red Sandalwood) is an important medicinal plant known for its diverse bio active compounds. Evaluation of its phytoconstituents is essential for ensuring its therapeutic potential and quality. Chromatographic and mass spectrometric techniques are effective tools for profiling

Acute Toxicity Study of Novel Ayurvedic Formulation Siddha Shalmali Kalpa (Classical Shalmali malabarica formulation) in Wistar Rat in vivo Experimental Study
Background: Traditional Ayurvedic Herbal remedies have long been used to improve and revitalize reproductive health. Siddha Shalmali Kalpa (Classical Shalmali malabarica formulation) is one such formulation that has long been praised for its aphrodisiac qualities. Its safety profile is still not well supported by scien

Phytochemical Profiling and Bioactivity Assessment of Traditional Medicinal Plants as Innovative Therapeutics for Wound Care Applications
Background: The worldwide healthcare system faces significant challenges due to prevalence of chronic wounds worsen by antimicrobial resistant bacteria and polymicrobial biofilm. Objectives: This research aims to unravel antibacterial and antibiofilm potential of bark of Lodhra, Katphal, Bijak and heartwood of Khadir,
