Pharmacognosy Research
Journal Impact
(As per Journal Citation Reports 2026)
Category: Pharmacology, Toxicology and Pharmaceutics > Drug Discovery and Pharmaceutical Science
Sources: Journal Citation Reports from Clarivate, 2026 release.
Pharmacognosy Research
Volume 19, Issue 1 • 2027
Phytochemical Profiling and Inhibitory Impact of Piper nigrum and Syzygium aromaticum Extracts Targeting GH13 Family Amylases
Background: Inhibition α-amylase have been reportedly providing a novel way in diabetes and obesity management. Purpose: Research for the last decade has outlined on broad range of health beneficial of various condiments and it is evident that regular spicy food consumption in appropriate quantity is also the reason o
Shenmai Injection Attenuates Pressure Overload-Induced Cardiac Hypertrophy by Modulating HRAS
Background/Objectives: Pressure overload-induced cardiac hypertrophy is a critical pathological precursor in the development of heart failure. Shenmai Injection (SMI) is widely used to treat cardiovascular diseases. However, its anti-hypertrophic effects and underlying molecular mechanisms remain insufficiently elucida
Integrated Phytochemical and Chromatographic Analysis for Detection of Adulteration in Terminalia chebula Fruit Rind Powder
Background: Terminalia chebula Retz. is a well-recognized medicinal plant widely used in the Ayurveda and Siddha systems of medicine, wherein the fruit rind is designated as the official therapeutic component. Admixture of the nut (kernel) portion with fruit rind powder has become a growing concern due to increased dem
Green-Synthesized Tribulus terrestris-Mediated CuO Nanoparticle-Loaded CS/PVA Hydrogels: A Multifunctional Platform for Cancer Therapy and Antidiabetic Applications
Objectives: In this work, we report on the preparation of CuO nanoparticles using extract from Tribulus terrestris as a natural reducing and stabilizing agent, followed by the loading of the nanoparticles into the Chitosan/Poly (vinyl alcohol) (CS/PVA) hydrogel in order to design a multifunctional system for treating c
GC-MS Analysis of Bioactive Phytocompounds in Polyherbal Formulation Extracted Ointment Used in the Management of Wound Healing
Background: The scientific validation of traditional as well as proprietary Ayurvedic formulations is crucial for the purpose of healing of wound in chronic non healing wounds. Polyherbal Formulation Extracted Ointment, a proprietary formulation made up of Water-soluble extracts of Nirgundi patra, Amalaki Bark and Bhri
Characterization and Chromatographic Evaluation of Shatapushpadi Lepa
Background: Shatapushpadi Lepa is a traditional external application specified in Ayurveda. The composition that is advised for Vata-dominant inflammatory joint diseases. To determine quality, and therapeutic effectiveness, such a conventional formulation must be scientifically validated. Purpose: The present study is
GC-MS Analysis and Quality Evaluation of Dashmoola Kashaya
Background: Dashmoola Kashaya is ayurvedic polyherbal formulation prepared from roots of ten medicinal plants which are traditionally used in the management of disorders like inflammatory conditions, neuromuscular disorders, respiratory diseases and musculoskeletal pain. To validate the quality and pharmacological rele
Comparative Structural and Biophysical Profiling of Dengue Virus NS5 Methyltransferase Identifies DENV-4 as a Prioritized Antiviral Target
Background: The NS5 Methyltransferase (MTase) domain is essential for the capping and replication of dengue virus RNA and for the virus's evasion of the host immune response, making it a promising antiviral target. Purpose: To assess the structural and biophysical characteristics of the NS5 MTase across the four Dengu
Chemically Synthesized Urolithin-C Regulates Glucose Uptake in HepG2 Cells
Background: In recent years, the prevalence of diabetes has increased dramatically worldwide. Although several drugs are available for its management, their severe cytotoxic effects have created a need for safer and more effective alternatives. Urolithins (A, B, C, D, M5, M6, and M7) have gained attention due to their
High Performance Thin Layer Chromatography (HPTLC) Methods for Simultaneous Estimation and Quantification of Vasicine, Gallic acid, Piperine and Pterostilbene from Two Ayurvedic Formulations and Herbal Extracts
Background: High Performance Thin Layer Chromatography (HPTLC) is an advanced analytical technique used for the identification and quantification of marker compounds in Ayurvedic formulations. Aims and Objectives: The purpose of this study is to create and validate an HPTLC method for the simultaneous estimation and q
Daidzein Attenuates Allergic Asthma via NF-κB1 Downregulation and Cytokine Modulation: A Comprehensive Preclinical Evaluation
Background: Bronchial Asthma (BA) is a chronic inflammatory airway disorder strongly associated with immune system dysregulation. Daidzein, a natural isoflavone found in soy, exhibits well-documented anti-inflammatory and immunomodulatory activities, including inhibition of dendritic cell maturation and regulation of e
Comparative Analysis of Multi-Solvent Tinospora cordifolia Fresh and Dry Leaf Extract Using Advanced Analytical Approaches
Background: Tinospora cordifolia is used worldwide for its medicinal properties, but its bioactive phytoconstituents have been less explored. Objectives: The fresh and dry leaf extracts of Tinospora cordifolia, a traditional medicinal plant, were comparatively analysed for their phytochemical content and therapeutic p
Metabolomics Insight into PN01 and SA02: Anticancer Efficacy and Antidiabetic Enzyme Inhibition
Background: Cancer is a major global health problem, with nearly 10 million deaths recorded in 2020. Approximately 30% of cancers in low- and lower-middle-income nations stem from infectious agents like Human Papillomavirus (HPV). Cervical Cancer (CC03) and HPV is now current issue all over the world especially Pakista