ArticlesAbstractPharmacognosy Research,2023,16,1,161-171.DOI:10.5530/pres.16.1.21Published:December 2023Type:Original ArticleAuthors:Shaik Harun Rasheed, Ravi Kumar Vakkalagadda, Sayyad Mustak, and Sandip Sen Author(s) affiliations:Shaik Harun Rasheed, Ravi Kumar Vakkalagadda, Sayyad Mustak, Sandip Sen* School of Pharmacy, Guru Nanak Institutions Technical Campus, Khanapur, Ibrahimpatnam, Telangana, INDIA. Abstract:Background: Evidence shows that people have used medicinal plants and plant components to treat various conditions since ancient times. Asparagus racemosus have a wide range of therapeutic potential Antioxidant, anti-cancer, anti-fungal, anti-bacterial, and anti-inflammatory. Aim and Objectives: The current study sought to identify potential bioactive molecules present in the petroleum ether extract of Asparagus racemosus. Materials and Methods: The presence of different molecules was identified by Gas Chromatography. Mass spectroscopy and FTIR analysis confirmed the molecular structure. The identified molecule was analyzed for drug likeliness, bioactivity, and target prediction analysis by in silico approaches using Swiss ADME, Swiss target prediction, Oasis datawarior, and mole inspiration software. Results: The petroleum ether extract is the highest source of alkaloids and steroids. The molecule (5.beta.) Pregnane-3,20, beta.-diol, 14.alpha.,1, 8. alpha.-[4-methyl-3-oxo-(1-oxa-4-azabutane-1,4-diyl)]- diacetate was found in the highest concentration (37.33%). The identified molecule is steroidal. The in silico study exhibited good drug likeliness and therapeutic potential for the reported molecule. The molecule can be considered a potential therapeutic agent for the treatment of cancer and analgesic anti-inflammatory agents. Conclusion: The molecule (5.beta.) Pregnane-3, 20. beta.-diol, 14.alpha.,1, 8. alpha.- [4-methyl-3-oxo-(1-oxa-4-azabutane-1,4-diyl)]-,diacetate can be considered as poteintial therapeutic agent. Keywords:Asparagus racemosus, Drug likeliness, Gas chromatography, In silico study, Mass spectroscopy, Petroleum ether, Target prediction.View:PDF (1.02 MB) PDF Thumbnails Document Outline Search Document Find Toggle Sidebar Previous Next Page: Fullscreen Print Download Current View Zoom Out Zoom In Automatic Zoom Actual Size Fit Page Full Width 50% 75% 100% 125% 150% 200% More Information Less Information Close Click here to download the PDF file. Images Boiled egg diagram of molecules identified in Petroleum ether extract of Asparagus racemosus KeywordsAsparagus racemosusDrug likelinessGas chromatographyGas ChromatographyIn silico studyin silico studyMass spectroscopyMass SpectroscopyPetroleum etherTarget prediction. ‹ Isolation, Purification and Characterization of L-Carvone from Mentha longifolia Using Fractional Distillation and Quantified by Gas Chromatography up Evaluation of the Effect of Five Colombian Propolis Extracts on the Expression of Genes Associated with Cell Cycle and Inflammation in a Canine Osteosarcoma Cell Line ›