Melezitose a Potential of Bioactive Compound from Aqueous Extract of Indian Satavari: An Web Based in silico Study Utilizing GC-MS Analysis

Sandip Sen; Kalepu Swathi; Dubbasi Vishwanath; Bairam Ravindar; Mitta Chaitanya; Srinivas Cherukupally; Shapuram Tejasree; Hema Varaha Santhoshi Allu

Melezitose a Potential of Bioactive Compound from Aqueous Extract of Indian Satavari: An Web Based in silico Study Utilizing GC-MS Analysis

Articles

Abstract

Pharmacognosy Research,2024,16,4,887-896.

DOI:10.5530/pres.16.4.101

Published:October 2024

Type:Original Article

Authors:

Author(s) affiliations:

Sandip Sen^1,*, Kalepu Swathi², Dubbasi Vishwanath³, Bairam Ravindar⁴, Mitta Chaitanya², Srinivas Cherukupally⁵, Shapuram Tejasree⁶, Hema Varaha Santhoshi Allu⁷

¹Department of Pharmaceutical Chemistry, School of Pharmacy, Guru Nanak Institutions Technical Campus, Ibrahimpattnam, Telangana, INDIA.

²Department of Pharmaceutical Chemistry, Bojjam Narasimhulu Pharmacy College for Women, Saidabad, Hyderabad, Telangana, INDIA.

³Department of Pharmaceutics, Sree Dattha Institute of Pharmacy, Nagarjuna Sagar Road, Sheriguda, Ibrahimpatnam. Telangana, INDIA.

⁴Department of Pharmaceutical Chemistry, Srikrupa Institute of Pharmaceutical Sciences, Velikatta, Telangana, INDIA.

⁵Department of Pharmacology, Nalla Narsimha Reddy College of Pharmacy, Chowdariguda, Narapally, Korremula X Road, Hyderabad, Telangana, INDIA.

⁶Department of Pharmacology, Vijaya College of Pharmacy, Hayathnagar, Thorrur, Hyderabad, Telangana, INDIA.

⁷Department of Pharmacy, Avanthi Institute of Pharmaceutical Sciences, Cherukupally, Vizianagaram, Andhra Pradesh, INDIA.

Abstract:

Background: Historical records indicate that medicinal plants and their components have been utilized for treating diverse conditions since antiquity. Asparagus racemosus, in particular, demonstrates a broad spectrum of therapeutic possibilities. Aim: This study aimed to pinpoint potential bioactive compounds found within the aqueous extract of Asparagus racemosus. Materials and Methods: Gas Chromatography employed to identify the presence of various molecules, while Mass Spectrometry and FTIR analysis validated their molecular structures. The molecule was subjected to thorough scrutiny for its potential as a drug candidate, its biological activity, and its predicted targets using in silico techniques. Results: The aqueous extract stands out as the richest reservoir of carbohydrates and steroidal alkaloids. The molecule Melezitose was found in the highest concentration (37.86%). The identified molecule is a carbohydrate in nature. The computational analysis revealed promising drug-like properties and therapeutic potential for the investigated molecule. Conclusion: It could serve as a viable therapeutic option for addressing multiple disorders.