%0 Journal Article %J Pharmacognosy Research %D 2011 %T Chemical Constituents and Biological Studies of Origanum vulgare Linn. %A Gottumukkala Venkateswara Rao %A T. Mukhopadhyay %A T. Annamalai %A N. Radhakrishnan %A M. R. Sahoo %K Origanol A and B %K Origanum vulgare Linn. %K Triterpene acids %K Tyrosinase inhibition %K β-sitosterol %X

Bioassay-guided isolation of methanolic extract of the leaves of Origanum vulgare Linn., yielded two protocatechuic acid ester derivatives, origanol A (1) and origanol B (2) along with ursolic acid (3), oleanolic acid (4), β-sitosterol (5), and triacontanol (6). Structures of the compound were established based on physical and spectral data (UV, IR, 1H and 13C NMR and mass). Origanol A (1) showed significant mushroom tyrosinase inhibition activity.

%B Pharmacognosy Research %V 3 %P 143-145 %8 June 2011 %G eng %N 2 %9 Short Communication %& 143 %R 10.4103/0974-8490.81964