01904nas a2200265 4500008004100000245010900041210006900150260001800219300001200237490000600249520111600255653001801371653001501389653001401404653002601418653002601444100001601470700001801486700002101504700001401525700001401539700001901553700001701572856004901589 2009 eng d00aBiological activity of two red algae, Gracilaria salicornia and Hypnea flagelliformis from Persian Gulf.0 aBiological activity of two red algae Gracilaria salicornia and H cJanuary 2010 a428-4300 v13 a
Among marine organisms, algae are a large and diverse group of organisms from which a wide range of secondary metabolites have been isolated. A number of these compounds possess biological activity. In this study, we aim to evaluate the cytotoxic, antibacterial and antifungal activity of two red algae, Gracilaria salicornia and Hypnea flagelliformis, collected from Persian Gulf. Ethyl acetate extracts of both algae showed a potent cytotoxic effect against Artemia salina nauplii (LC50 = 3 and 4 μg.ml−1, respectively). Aqueous methanol (50%) extracts were also effective. None of the methanol and aqueous methanol extracts of the algae showed antifungal and antibacterial activity against Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger by the Broth-dilution method. Only the ethyl acetate extracts exhibited antibacterial activity (MIC = 2 μg.ml−1) on S. aureus. In conclusion, G. salicornia and H. flagelliformis could be a promising source of cytotoxic components.
10aAntibacterial10aAntifungal10aCytotoxic10aGracilaria salicornia10aHypnea flagelliformis1 aS, Saeidnia1 aR, Gohari, A.1 aR, Shahverdi, A.1 aP, Permeh1 aM, Nasiri1 aK., Mollazadeh1 aF., Farahani uhttps://phcogres.com/article/2009/1/6/nil-16