01682nas a2200205 4500008004100000245012400041210006900165260001400234300001200248490000600260520096300266653004401229653001801273653002101291653004101312100001801353700001401371700002801385856006301413 2010 eng d00aThe Antihyperglycemic Effect of Aerial Parts of Salvia splendens (scarlet sage) in Streptozotocin-induced Diabetic-rats0 aAntihyperglycemic Effect of Aerial Parts of Salvia splendens sca cJuly 2010 a190-1940 v23 a

Salvia splendens (Labiatae) is widely used in Indian traditional medicine for the control of diabetes mellitus. In this study, the hypoglycemic effects produced by the acute and subacute administration of various extracts of S. splendens were investigated. Both the aqueous extract (SSAE) and the methanolic extract (SSME) from the aerial parts resulted in significant reductions of glycemia in streptozotocin (STZ)-induced diabetic rats after oral administration at a dose of 100 and 200 mg/ kg, respectively. On oral administration, aqueous and methanolic extracts showed statistically significant (P < 0.001) effect by reducing the effect of glycemia in STZ-induced diabetic rats. These findings suggest the significant antihyperglycemic potential of the S. splendens extracts in ameliorating the diabetic conditions in diabetic rats. No significant effects were found in the normal rats.

10aAcute and subacute antidiabetic studies10aGlibenclamide10aSalvia splendens10aStreptozotocin-induced diabetic rats1 aKumar, Mahesh1 aSasmal, D1 aMazumder, Papiya, Mitra uhttps://phcogres.com/article/2010/2/3/1041030974-849065520