02436nas a2200229 4500008004100000245009700041210006900138260001800207300001200225490000600237520173300243653001601976653002401992653001902016653002102035653001302056100002002069700001902089700002102108700002902129856004802158 2009 eng d00aModulatory Effect of Erythrina vareigata on Experimental Hyperlipidaemia in Male Wistar Rats0 aModulatory Effect of Erythrina vareigata on Experimental Hyperli cJanuary 2010  a202-2070 v13 a

Erythrina vareigata is a medium sized quick growing tree found distributed in deciduous forests throughout India. Its leaves are eaten as a pot herb and different parts of the plant have folkloric reputation as an anti inflammatory in India, China and South east Asia. Bark, wood, root and flowers are richly represented by isoflavones, pterocarpans and biphenyls. Current investigations were aimed at evaluating the hypolipidaemic activity of this popular hypolipidaemic siddha drug. Its nutritive value was estimated by standard reported methods. Ethyl acetate extract of the dried leaves were analyzed for total phenol content by Folin Ciocalteau and Titanium tetrachloride method. Its in vitro anti oxidant activity was assessed by DPPH, NO and trichloroacetic acid based reducing power method. Male wistar rats were subjected to high fat diet induced (HFD) hyperlipidaemia concurrent with extract administration for 60 days. While normal control group received standard pellet diet, Positive control group was on HFD only. At the end of experimentation, blood was collected for serum estimation of total cholesterol, high density lipoprotein cholesterol, triglycerides and atherogenic index. The extract had a high total phenol content, beneficially altered lipid parameters and reduced body weight of experimental animals. The leaves are rich in protein, minerals, vitamins and low in carbohydrate and fat. Anti oxidant activity of the polyphenols present in the extract might be mediating the observed hypoplipidaemia. This study validated the traditional medicine claims of its anti obesity effect as well as folkloric tutelage of consumption of leaves as a green vegetable.

10aAntioxidant10aErythrina vareigata10aHypolipidaemic10aPhenolic content10aPot herb1 aK, Mangathayaru1 aK, Balakrishna1 aSarah, Kuruvilla1 aMaheshwara, Reddy, C Uma uhttps://phcogres.com/article/2009/1/4/nil-7