02443nas a2200217   4500008004100000245014300041210006900184260001300253300001200266490000600278520173400284653002502018653001602043653001402059653001902073653001302092653001802105100001602123700002302139856006302162       2010                        eng d00aAntimicrobial Properties, Antioxidant Activity and Bioactive Compounds from Six wild Edible Mushrooms of Western Ghats of Karnataka, India0 aAntimicrobial Properties Antioxidant Activity and Bioactive Comp  cMay 2010  a107-1120 v23 a<p class="rtejustify">Methanolic extracts of 6 wild edible mushrooms isolated from the Western Ghats of Karnataka were used in this study. Among the isolates <em>(Lycoperdon perlatum, Cantharellus cibarius, Clavaria vermiculris, Ramaria formosa, Marasmius oreades, Pleurotus pulmonarius),</em> only 4 showed satisfactory results. Quantitative analysis of bioactive components revealed that total phenols are the major bioactive component found in extracts of isolates expressed as mg of GAE per gram of fruit body, which ranged from 3.20 ± 0.05 mg/mL to 6.25 ± 0.08 mg/mL. Average concentration of flavonoid ranged from 0.40 ± 0.052 mg/mL to 2.54 ± 0.08 mg/mL; followed by very small concentration of ascorbic acid (range, 0.06 ± 0.01 mg/mL to 0.16 ± 0.01 mg/mL) in all the isolates. All the isolates showed high phenol and flavonoid content, but ascorbic acid content was found in traces. Antioxidant efficiency by inhibitory concentration on 1,1-Diphenly-2-picrylhydrazyl (DPPH) was found significant when compared to standard antioxidant like Buthylated hydroxyanisol (BHA). The concentration (IC <sub>50</sub> ) ranged from 0.94 ± 0.27 mg/mL to 7.57 ± 0.21 mg/mL. Determination of antimicrobial activity profile of all the isolates tested against a panel of standard pathogenic bacteria and fungi indicated that the concentrations of bioactive components directly influence the antimicrobial capability of the isolates. Agar diffusion assay showed considerable activity against all bacteria. Minimum inhibitory concentration values of the extracts of 4 isolates showed that they are also active even in least concentrations. These results are discussed in relation to therapeutic value of the studied mushrooms.</p>
10aAgar diffusion assay10aAntioxidant10aBioactive10aDPPH mushrooms10ain-vitro10aWestern Ghats1 aRamesh, Ch.1 aPattar, Manohar, G  uhttps://phcogres.com/article/2010/2/2/1041030974-849062953