01637nas a2200181 4500008004100000245011000041210006900151260001800220300001200238490000600250520106500256653001601321653001201337653001901349653002101368100002001389856004601409 2009 eng d00aEffect of Methyl Jasmonate on Production of Ariltetralin Lignans in Hairy Root Cultures of Linum tauricum0 aEffect of Methyl Jasmonate on Production of Ariltetralin Lignans cJanuary 2010  a102-1050 v13 a

Methyl jasmonate (MeJA) treatment increases the levels of plant secondary metabolites, including ariltetraline lignans, which are considered to be the main active compounds in Linum tauricum. This study was concentrated on the induction of production of ariltetralin lignans in hairy roots cultures of L. tauricum, transformed by Agrobacterium rhyzogenes, ATCC 15834 by exposing them to different concentrations (50-200 microM) of methyl jasmonate (MeJA) during the culture period. The content of 4'-demethyl-6-methoxypodo-phylotoxin (4'-DM- 6MPTOX) and 6-methoxypodophyllotoxin (MPTOX), the main constituents in hairy roots of L. tauricum increased about 1.2 folds by elicitation of MeJA, however, the fresh weight, dry weight and growth ratio was inhibited by increasing MeJA concentrations. The highest total lignans yield was obtained with 150 microM MeJA treatment. These results suggest that MeJA elicitation is beneficial for lignan accumulation in the hairy roots cultures of L. tauricum.

10aHairy roots10aLignans10aLinum tauricum10aMethyl jasmonate1 aIonkova, Iliana uhttps://phcogres.com/article/2009/1/3/nil