01909nas a2200193 4500008004100000245007900041210006900120260001800189300001000207490000600217520125100223653008001474653002001554100002001574700002001594700003001614700002301644856004801667 2009 eng d00aNew secoiridoids from Ligustrum ovalifolium and their hypotensive activity0 aNew secoiridoids from Ligustrum ovalifolium and their hypotensiv cJanuary 2010  a91-970 v13 a

New Secoiridoid glucosides 1-5; ligustaloside A methyl hemiacetal 1, ligustaloside B methyl hemiacetal 2, ligustaloside A dimethyl acetal 3 ligustaloside A butyl-methyl acetal 4, and ligustaloside B butyl hemiacetal 5 have been isolated from the leaves of Ligustrum ovalifolium L. along with five known secoiridoids; ligustaloside B dimethyl acetal 6, 10-hydroxy oleuropein 7, 10-hydroxy ligstroside 8, oleuropein 9 and ligstroside 10, one known iridoid; loganin 11 and two known phenethyl alcohol glucosides; 3,4-di hydroxyphenylethyl--D-glucoside 12 and p-hydroxyphenylethyl--D-glucoside 13. The structures have been elucidated by spectroscopic means including 1D NMR (1H, 13C, and DEPT), 2D NMR (COSY, HMQC and HMBC experiments), UV, IR and FAB-MS (positive mode). Both n-BuOH fraction and the isolated new compounds 1-5 were evaluated for their hypotensive activity on experimental animal. The n-BuOH fraction showed good activity; however, the activity of the isolated new compounds 1-5 did not particularly strong.

10aLigustrum ovalifolium; Oleaceae; Secoiridoid glucosides; Lridoid glucosides10aPhenylethanoids1 aHosny, Mohammed1 aRagab, Ehab, A.1 aMohammed, Abd, El-salam I1 aShaheen, Usama, Y. uhttps://phcogres.com/article/2009/1/2/nil-5