02375nas a2200253 4500008004100000245008700041210006900128260001500197300001200212490000600224520155400230653001601784653002001800653002801820653002601848653002401874653002901898100002801927700002201955700002801977700002802005700002402033856006402057 2014 eng d00aAphrodisiac Activity of Polyherbal Formulation in Experimental Models on Male Rats0 aAphrodisiac Activity of Polyherbal Formulation in Experimental M cMarch,2014 a120-1260 v63 a

Objective: To investigate the aphrodisiac potential of polyherbal formulations prepared from different parts of Tribulus terrestris, Curculigo orchioides, Allium tuberosum, Cucurbita pepo, Elephant creeper, Mucuna pruriens, and Terminalia catappa in Albino rats in specified ratio as suspension. Materials and Methods: The different concentrations of prepared polyherbal formulations i.e. 150, 300, and 600 mg/kg and sildenafil citrate as standard (5 mg/kg) and vehicle (control) were administered orally to rats (n = 6 animals per group) for 3 weeks. Mating behavior parameters in male rats was monitored in first week and third week week of treatment pairing with receptive females. After termination of drug treatment, the mating performance, hormonal analysis, sperm count, and testes-body weight ratio were also evaluated. Results: The polyherbal formulation showed a significant increase in mating behavior as well as mating performance, serum hormonal levels, sperm count, and testes-body weight ratio with dose-dependent relationship as compared to vehicle control. But the dose of 600 mg/kg of polyherbal formulation assumes closer resemblance of above parameters with the standard used. Conclusion: The results of the study strongly suggest that the polyherbal formulations have a good aphrodisiac activity on rats in the above experimental models, which may be an alternative weapon for various sexual dysfunctions in future.

10aAphrodisiac10aMating behavior10aPolyherbal formulations10aSerum hormonal levels10aSexual dysfunctions10aTestes-body weight ratio1 aSahoo, Himanshu, Bhusan1 aNandy, Subhangkar1 aSenapati, Aswini, Kumar1 aSarangi, Sarada, Prasad1 aSahoo, Saroj, Kumar uhttps://phcogres.com/article/2014/6/2/1041030974-8490129029