02438nas a2200193 4500008004100000245008600041210006900127260001800196300001000214490000600224520180000230653001902030653002302049653002002072653003202092100003202124700002502156856006302181 2012 eng d00aGC-MS Analysis of Phytocomponents in the Ethanol Extract of Polygonum Chinense L.0 aGCMS Analysis of Phytocomponents in the Ethanol Extract of Polyg cdecember,2011 a11-140 v43 a

Background: The presence of diverse secondary metabolites has been reported from species of the genus Polygonum. However, there has been not much information available on phytochemical components and biological activity in the whole plant ethanol extract of Polygonum chinense L. Objective: This study was designed to determine the phytocomponents in the whole plant ethanol extract of P. chinense. Materials and Methods: GC-MS analysis of the whole plant ethanol extract of P. chinense was performed using a Perkin-Elmer GC Clarus 500 system comprising an AOC-20i auto-sampler and a gas chromatograph interfaced to a mass spectrometer (GC-MS). Results: This investigation was carried out to determine the possible chemical components from P. chinense by GC-MS. This analysis revealed that the ethanol extract of P. chinense (whole plant) contained mainly a triterpene compound-squalene (47.01%), and a plasticizer compound-1,2-benzenedicarboxylic acid, mono[2-ethylhexyl]ester (40.30%). All identified compounds were, generally, reported as having antimicrobial activity. In addition, the squalene compound also having anti-cancer, anti-oxidant, anti-tumor, chemo-preventive, pesticidal and sun-screen properties, while the plasticizer compound -1,2-benzenedicarboxylic acid, mono[2-ethylhexyl] ester reported to have anti-oxidant and anti-inflammatory properties. No activity was reported in the alcoholic compound-4-hexene-1-ol, 5-methyl-2-(1-methylethanyl)-acetate-(R)-. Conclusions: From the results, it is evident that P. chinense contains various bioactive compounds and is recommended as a plant of phytopharmaceutical importance.

10aGC-MS Analysis10aPolygonum chinense10aRhytocomponents10aWhole plant ethanol extract1 aEzhilan, Bagavathi, Perumal1 aNeelamegam, Ramasamy uhttps://phcogres.com/article/2012/4/1/1041030974-849091028