01823nas a2200157 4500008004100000245011300041210006900154260001400223300001200237490000600249520130200255653000801557100001901565700001801584856006301602 2012 eng d00aThe Effects of Aqueous Extract of Cleistanthus Collinus (Roxb.) (Euphorbiaceae) Leaves On Rat Blood Pressure0 aEffects of Aqueous Extract of Cleistanthus Collinus Roxb Euphorb cJuly,2012 a178-1800 v43 a

The genus Cleistanthus (Euphorbiaceae) comprises about 140 species which includes Cleistanthus collinus, Cleistanthus patulus, Cleistanthus schlechteri, and Cleistanthus gracili.[1] Cleistanthus collinus (Roxb.) Benth. ex Hook. f. (Euphorbiaceae) is known as a toxic plant and found in Africa, India, Sri Lanka, and Malaysia.[2] In India, this plant is commonly used as a suicidal poison. All parts of the plant are reported to be toxic and used as suicidal, homicidal, cattle and fish poison and for inducing criminal abortion.[3] In patients, the clinical manifestations of C. collinus poisoning include hyperthermia, hypokalemia, ECG abnormalities (prolongation of QT interval, ST depression, and flat P wave), and elevation of hepatic enzymes such as alkaline phosphatase (ALP), serum glutamic pyruvic transaminase (SGPT), and serum glutamic oxaloacetic transaminase (SGOT).[2] In some clinical cases, a water decoction of C. collinus causes fall in blood pressure.[2] Hence, this study was planned to determine the effects of aqueous extract of C. collinus leaves on rat blood pressure using an invasive procedure. Read More ....

10aNil1 aParasuraman, S1 aRaveendran, R uhttps://phcogres.com/article/2012/4/3/1041030974-849099086