01751nas a2200229 4500008004100000245009300041210006900134260001800203300001000221490000600231520102600237653001701263653002001280653002101300653002401321100002501345700002001370700002001390700002401410700002301434856006401457 2015 eng d00aEvaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity0 aEvaluation of Bacillus cereus and Bacillus pumilus metabolites f cDecember 2014 a81-840 v73 a

Objective: To assess the anthelmintic acivity of Bacillus cereus and Bacillus pumilus metabolites. Materials and Methods: The successive solvent extractions with petroleum ether, ethyl acetate and methanol. The solvent extracts were tested for anthelmintic activity against Pheretima posthuma at 20 mg/ml concentration. The time of paralysis and time of death of the worms was determined for all the extracts. Albendazole was taken as a standard reference and sterile water as a control. Results: All the sample extracts showed significant anthelmintic activity in paralyzing the worms comparable with that of the standard drug. The time of death exhibited by BP metabolites was close to the time exhibited by standard. Conclusion: The study indicates both bacteria Bacillus cereus and Bacillus pumilus have anthelmintic activity indicating potential metabolites in them.

10aAnthelmintic10aBacillus cereus10aBacillus pumilus10aPheretima posthuma.1 aKumar, M., L. Vijaya1 aThippeswamy, B.1 aKuppust, I., L.1 aNaveenkumar, K., J.1 aShivakumar, C., K. uhttps://phcogres.com/article/2015/7/1/1041030974-8490147213