02442nas a2200217 4500008004100000245008500041210006900126260001500195300001200210490000700222520178000229653001302009653002002022653001302042653003302055653001302088100001902101700001602120700002902136856005902165 2019 eng d00aEfficacy of Topical Herbal Remedies for Insomnia in Iranian Traditional Medicine0 aEfficacy of Topical Herbal Remedies for Insomnia in Iranian Trad cApril 2019 a188-1910 v113 a

Background: Insomnia is one of the most prevalent sleep disorders which affect the quality of life. Due to high prevalence of this disease and the side effects of sedative drugs, people tend to use herbal remedies. There are some oral or topical prescriptions in Persian medicine texts for the treatment of insomnia. The aim of this study was to investigate topical treatments for insomnia in Iranian traditional medicine (ITM) and comparing them with current therapies in modern medicine. Materials and Methods: In this study, ITM textbooks including the Canon of Medicine, Teb‑e‑Akbari, Kholasat al‑Hekmah, Makhzan al‑Advieh, Exir‑e‑azam, Al‑Aghraz al‑Tibbia, Val Mabahess al‑Alaiia, Sharh-al-Asbab-val-Alamat, Tohfa‑al‑Momen, and Qarabadeen‑e‑Kabir were searched to investigate effective topical therapies for treating insomnia. Further, relevant studies on these topical remedies were searched at databases such as PubMed, Google Scholar, Scopus, and ScienceDirect from the beginning till June 2018 and the results were presented as tables. Results: There are some herbs which have been recommended in ITM for the treatment of insomnia in topical dosage form such as ointment, lotion, nasal drop, and oil. The most important herbs used in these topical dosage forms were lettuce, violet, almond, pumpkin, and water lily. Some of these herbal therapies including lettuce and violet have been studied in clinical trial for insomnia. Conclusion: Findings of the present study showed that according to ITM texts, there are some effective topical herbal remedies which can be used in treatment of insomnia with less adverse effects.

10aEfficacy10aHerbal medicine10aInsomnia10aIranian traditional medicine10aTopical.1 aHaghjoo, Elham1 aShoja, Asie1 aParvizi, Mohammad, Mahdi uhttps://phcogres.com/article/2019/11/2/104103prpr16318