02119nas a2200265   4500008004100000245013800041210006900179260001700248300001200265490000700277520122500284653002401509653002601533653002101559653001801580653001301598653001201611100003001623700003201653700002201685700003001707700003101737700002501768856006001793       2023                        eng d00aPlant-Derived Selected Bioactive Saponins and Tannins: An Overview of their Multi-Target Mechanisms and Diverse Biological Activities0 aPlantDerived Selected Bioactive Saponins and Tannins An Overview  cOctober 2023  a623-6350 v153 a<p class="rtejustify">An extensive variety of ailments have been treated using medicinal herbs for ages. Recent research has revealed that many of these plants possess multiple therapeutic activities, rendering them interesting candidates for the creation of novel medicines. This review examines the current state of knowledge regarding the multi targeted activities of medicinal plants, including their potential for treating multiple diseases like anti-inflammatory, anti-microbial, anti-hyperglycaemic and anti-cancer activities, their ability to modulate multiple pathways, enzymes, genes and proteins. Finally, the review highlights the potential of naturally derived substances from plant material, for the development of multitargeted drugs and suggests strategies for further research. The multi-target activities will be thoroughly explored in this review of ginsenosides, platycodon D, dioscin, soyasaponins and aescin were chosen as saponins, whereas methyl gallate, chebulinic acid, tannic acid, theaflavin and punicalagins were chosen as tannins. This overview gives a brief history of the isolated natural compounds, their structures, multi-target activity, and their suggested mechanisms of action.</p>
10aBioactive compounds10aBiological activities10aMedicinal plants10aMulti targets10asaponins10aTannins1 aVyshnavi, Dudday, Venkata1 aSwaroop, Sunkara, Sivananda1 aSudheer, Akkiraju1 aKanala, Somasekhar, Reddy1 aNaik, Ramavath, Muralidhar1 aVaralakshmi, Onamala  uhttps://phcogres.com/article/2023/15/4/105530pres154066