02803nas a2200229 4500008004100000245013400041210006900175260001300244300001300257490000700270520201200277653001802289653002402307653003802331653002302369653003202392100002202424700002302446700002102469700002402490856005902514 2020 eng d00aPharmacognostical Standardization, Phytochemical Investigation, and Anthelminthic Activity of Arisaema propinquum Schott Rhizomes0 aPharmacognostical Standardization Phytochemical Investigation an cMay 2020 a 181-1850 v123 a

Ethnopharmacology: Arisaema propinquum Schott (Araceae) is commonly known as cobra lily. Traditionally, the rhizomes were used as vermifuge, in rheumatism, as stomachache, and in snake bites. Objectives: The present study was designed to evaluate the pharmacognostical parameters and anthelminthic activity of A. propinquum rhizomes. Materials and Methods: The rhizomes of A. propinquum Schott was collected, shade dried and then powdered, and then evaluated for pharmacognostic parameters such as macro- and microscopical characters, physico-chemical parameters, and phytochemical analysis using standard procedures. Anthelminthic activity of the extracts was elevated against Pheretima posthuma. Results: The rhizomes are light brown in color with pungent odor and astringent taste. Transverse section of rhizomes showed intercellular schizogenous cavities, xylem vessels, phloem vessels, and parenchymatous cells. Phytochemical screening of the extracts reveals the presence of alkaloids, carbohydrates, cardiac glycosides, coumarins, proteins, amino acids, phenols, tannins, flavonoids, saponins, steroids, and terpenoids. Physiochemical parameters including ash values showed 6.32% total ash, 1.77% acid insoluble ash, 5.15% water-soluble ash, and 8.55% sulfated ash. Other parameters such as extractive value, foreign matter, moisture content, swelling index, foaming index, pH of different solvents, and fluorescence analysis were also determined. Both the methanolic and aqueous extracts of A. propinquum showed dose-dependent anthelminthic activity against P. posthuma compared to standard albendazole. Conclusion: This is the first report on the pharmacognostic studies and anthelminthic activity of A. propinquum Schott. Data composed from such studies can be used as a standard in the quality control of this plant used as an herbal medicine for the treatment of various diseases.

10aAnthelminthic10aArisaema propinquum10aPharmacognostical standardization10aPheretima posthuma10aPhytochemical investigation1 aMir, Prince, Ahad1 aMohi-ud-din, Roohi1 aDar, Mohd, Akbar1 aBader, Ghulam, Nabi uhttps://phcogres.com/article/2020/12/2/104103prpr10619