@article {1219, title = {A Comprehensive Review of Therapeutical and Ethnobotanical Aspects, Phytoconstituent and Pharmacological Activity of Aesculus indica}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {April 2024}, pages = {203-210}, type = {Review Article}, chapter = {203}, abstract = {

Aesculus indica Wall. Ex Camb. Hook, a member of the Hippocastanaceae family, exhibits robust growth in colder climates worldwide, showcasing its remarkable adaptability. Within its various components lie a diverse array of constituents, each harboring a treasury of advantageous compounds that have found utility across a spectrum of applications. These applications encompass the amelioration of gastrointestinal disturbances, facilitation of hemostasis, management of diabetes, and mitigation of various dermatological afflictions. Through a comprehensive synthesis of information gleaned from an array of authoritative sources including meticulous literature surveys, our study provides a thorough dissection. It traverses the multifaceted tapestry of this plant{\textquoteright}s applications, devlopes into its intricate chemical composition, and elucidates its nuanced effects on human health and well-being. This compendium stands as an invaluable reservoir, poised to aid and embolden scientists and researchers engaged in the exploration of natural products. Its content, meticulously aggregated and meticulously crafted, promises a resourceful springboard for their scholarly inquiries while assuring originality and authenticity in their pursuits.

}, keywords = {Aesculus indica, Anti-diabetic activite, Antimicrobial activity., Antioxidant, Pharmacognosy, Pharmacology activity, Phytochemistry}, doi = {10.5530/pres.16.2.26}, author = {Shubham Anand and Arijit Chaudhuri and Neha Chopra and Devendra Dhanorya and Manoj Kumar Bajhaiya and Gujjala Sai Sri Harsha and Vijeta Bhattacharya and Udichi Kataria and Gaurav Kumar} } @article {1107, title = {Chemical Profile and Antimicrobial Activity of Syagrus oleracea (Mart.) Becc. Oils and Oils Extracted from Speciomerus revoili (Pic.) Larvae}, journal = {Pharmacognosy Research}, volume = {15}, year = {2023}, month = {December 2022}, pages = {71-74}, type = {Original Article}, chapter = {71}, abstract = {

Background: The antimicrobial effect of oils extracted from Syagrus oleracea (Mart.) to prove the action and obtain data for the future development of therapeutic products. Objectives: The present study was to determine the chemical profile and the antimicrobial potential of oils extracted from Syagrus oleracea (Mart.) Becc. almonds and Speciomerus revoilie (Pic.) larvae to obtain scientific information to prove the action and obtain data for the future development of therapeutic products. Materials and Methods: The separation, identification and quantification of fatty acids in oils extracted from the larvae of S. revoili (Coleoptera, Chrysomelidae) and almonds of S. oleracea (Arecaceae) were performed by gas chromatography coupled with mass spectrometry. The determination of antibacterial activity was performed using microdilution in plates. Results: In the oils extracted from S. revoili and S. oleracea, saturated chain fatty acids, the presence of hexanoic acid (only in almonds), and caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid and those of unsaturated chain, oleic acid (omega-9) and linoleic acid (omega-6). S. revoili oil showed satisfactory results against Escherichia coli and Staphylococcus aureus.

}, keywords = {Antimicrobial activity., Fatty acids, Speciomerus revoili, Syagrus oleracea}, doi = {10.5530/097484900265}, author = {Luciana Helena Veloso and Dario Alves de Oliveira and Cintya Neves de Souza and Francine Souza Alves and Vany Ferraz and Anna Christina de Almeida and Afr{\^a}nio Farias de Melo J{\'u}nior and Elytania Veiga Menezes and Murilo Malveira Brand{\~a}o and Vanessade Andrade Royo} } @article {1151, title = {Formulation and Evaluation of Phytosomes of Hydroalcoholic Extract of Adiantum capillus-veneris for Antimicrobial Activity}, journal = {Pharmacognosy Research}, volume = {15}, year = {2023}, month = {June 2023}, pages = {468-477}, type = {Original Article }, chapter = {468}, abstract = {

Background: Natural plant extracts and phytoconstituents have high in vitro bioactivity but low in vivo bioactivity because of poor lipid solubility, multiple ring large molecules, or digestion in the gut. Polyphenolic phytoconstituents were complexed with phospholipids, mainly phosphatidylcholine, which molecularly attaches components to one another to produce novel drug delivery systems like phytosomes. The important constituents of the herbal extract are designed to protect from being disrupted by gastric juices and gut bacteria, as phytosomes have the ability to cross the bio-membranes that which are lipid enriched and boost bioavailability. Objectives: The current work is aimed to formulate and evaluate phytosomes from Adiantum capillus-veneris (ACV) hydroalcoholic extract for antimicrobial activity. Materials and Methods: Antisolvent precipitation method was chosen on the basis of the solubility of hydroalcoholic extract in dichloromethane. The prepared trial batches of the phytosomes complex were characterized by using particle size, zeta potential, drug entrapment efficiency, drug content, and in vitro drug release study. The optimized batch of phytosomes was characterized for compatibility studies by using Infrared Spectrometry (IR), Transmission Electron Microscopy (TSM), Differential Scanning Calorimetry (DSC), and further for stability studies. Results: The results revealed that ACV hydroalcoholic extract and phosphatidylcholine were found to be connected by a non-covalent bond and did not generate a new molecule in the ACV hydroalcoholic extract-phosphatidylcholine complex and showed enhanced in vitro antimicrobial activity as compared to the hydroalcoholic extract. Conclusion: The complex{\textquoteright}s dissolution profile was found to be improved. As a result, the phospholipid complex of ACV extract can therefore be concluded to have the potential to enhance bioavailability.

}, keywords = {Adiantum capillus-veneris (ACV), Antimicrobial activity., H-ACV extract phytosomes, Hydroalcoholic extract, Phytosomes}, doi = {10.5530/pres.15.3.048}, author = {Supriya Ganesh Jagtap and Vedant Vinay Kajale and Mukta Mahesh Abhyankar and Aditi Shrinivas Kulkarni and Minal Rushikesh Ghante} }