@article {1310, title = {Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {October 2024}, pages = {706-717}, type = {Review Article}, chapter = {706}, abstract = {

Herbal hepatoprotective drugs are important for managing liver health because they provide complementary or alternative treatments for the various disorders of the liver. This review provides a thorough analysis of the numerous herbal hepatoprotective drugs{\textquoteright} studied during the recent years, including their modes of action, suggested dosages, market trends, status of clinical trials and patents. The hepatoprotective properties of these herbal medicinal products are partly attributed to their mechanisms of actions such as antioxidant, anti-inflammatory, enzyme-modulating actions, and regeneration of hepatocytes. The recommended dosages differ based on the particular plant and ailment, highlighting the necessity for individualized treatment plans and more research to achieve the best possible therapeutic results. Patented compositions and polyherbal formulations provide novel treatments with synergistic effects that improve medicinal efficacy. The increased demand for natural treatments and their potential applications in pharmaceutical and nutraceutical fields has resulted in a considerable and expanding market for herbal hepatoprotective agents. Notwithstanding their possible advantages, more investigation is required to clarify mechanisms of action, assess long-term safety and efficacy, and provide uniform standards for clinical application. In general, herbal hepatoprotective drugs are promising approaches to manage liver health; nonetheless, their use necessitates regulatory oversight, quality control procedures, and evidence-based practice.

}, keywords = {Dosage, Hepatoprotective Agents, Herbal drugs, Market Size, Mechanism, Patents}, doi = {10.5530/pres.16.4.82}, author = {Rajendra Prasad Menasagere Rajappa and Paramakrishnan Nallupillai and Kamsagara Linganna Krishna and Manoj Madanahalli Ramesh and Annegowda Hardur Venkatappa} } @article {987, title = {Phytochemical and GC-MS Analysis of Hydro Ethanolic Leaf Extract of Ocimum sanctum (L.)}, journal = {Pharmacognosy Research}, volume = {13}, year = {2021}, month = {October 2021}, pages = {233-237}, type = {Original Article}, chapter = {233}, abstract = {

Background: The pharmacological efficiency of herbal drugs has shown to be effective as conventional pharmaceutical drugs. Preliminary screening of herbal extracts helps in analysing the bioactive compounds present. Ocimum sanctum, the queen of herbs keeps a spiritual importance in Indian culture and have important place in traditional medicinal system of India. Objectives: The present study was implement to investigate the preliminary phytochemical screening and GC-MS analysis of leaf extract of O. sanctum to determine the phytoconstituents. Materials and Methods: Leaves collected were dried, crushed and mixed with ethanol and water and further applied for extract preparation. The prepare extract was used for phytochemical and GC-MS analysis. Results: In qualitative phytochemical analysis tannins, carbohydrate, quinine, anthraquinones, coumarins, phlobatanins, alkaloids, flavonoids, glycosides, terpenoids, diterpenes, phenols were found present while GC-MS analysis showed Eugenol, Cyclohexane, bicyclo[7.2.0]undec-4-ene, 4,11,11-trimethyl-8-methylene, Oxatricyclo[ 8.2.0.0(4,6)]dodecane,,12-trimethyl-9-methylene, Tetracontane, Phytol were present in majority. Conclusion: The study concluded that O. sanctum leaf extracts contain many biological active compounds which could be exploited for a development of plant based drug.

}, keywords = {Flavonoids, GC-MS Analysis, Herbal drugs, Phenolics, Phytochemical}, doi = {10.5530/pres.13.4.16}, author = {Atul Srivastava and Subhashini and Anand Kumar Keshari and Ragini Srivastava} }