@article {1019, title = {Comparative Macroscopic and Microscopic Characterization of Raw Herbal Drugs of Abrus precatorius L. and Glycyrrhiza glabra L.}, journal = {Pharmacognosy Research}, volume = {14}, year = {2022}, month = {December 2021}, pages = {100-106}, type = {Original Article}, chapter = {100}, abstract = {

Background: The root of Glycyrrhiza glabra L., also known as {\guilsinglleft}Licorice,{\textquoteright} is used as an expectorant in cough and cold preparations, used to treat hepatitis, and have therapeutic benefit against some other viruses. The roots of Abrus precatorius L. belonging to the family Leguminosae are commonly known as {\textquoteleft}Indian wild Licorice.{\textquoteright} The roots of both of these plants are used in Indian systems of medicine (I.S.M.) to treat various health ailments. The root of A. precatorius is used as a substitute or sometimes as an adulterant of G. glabra. Objectives: The present study aimed to develop comparative standards for easy and fast identification of root drug samples of two selected species. Materials and Methods: The present study involved a comparative macroscopic and microscopic characterization of the root drug samples of G. glabra and A. precatorius using compound and stereo microscopes. Results: Comparative study of qualitative and quantitative characters revealed significant differences in surface and microscopic characters. Anatomical characters such as cortex and phloem zone appearance, the appearance of vascular rays, and some powder characters, i.e., color and taste of powder and shape and size of starch grains, clearly differentiated the genuine {\textquoteleft}Liquorice{\textquoteright} drug root samples from other drug species. Conclusion: Botanical characters compiled in the present study can be used as a reference standard for future identification of individual raw root drug samples and the comparative distinction of both species{\textquoteright} root samples.

}, keywords = {Identification characters, Licorice, Macroscopic and microscopic studies, Raw root herbs, Reference standards.}, doi = {10.5530/pres.14.1.14}, url = {https://phcogres.com/fulltext/v14i1/105530pres14114.html}, author = {Pankaj Kumar and Javaid Fayaz Lone and Sumeet Gairola} } @article {844, title = {Effect of Licorice Versus Bismuth on Eradication of Helicobacter Pylori in Patients with Peptic Ulcer Disease}, journal = {Pharmacognosy Research}, volume = {6}, year = {2014}, month = {August,2014}, pages = {341-344}, type = {Original Article}, chapter = {341}, abstract = {

Background: Different therapeutic regimens were used for eradication of Helicobacter pylori, based on the cost, effectiveness and patient{\textquoteright}s compliance. The aim of this study was the evaluation of licorice compared with bismuth in quadruple regimen on eradication of H. pylori in patients with peptic ulcer disease (PUD). Materials and Methods: In a double-blind clinical trial study, 60 patients with PUD and positive rapid urease test were enrolled. The patients were randomly allocated into two equal groups. In first group, licorice, amoxicillin, metronidazole and omeprazole and in the second (control) group, bismuth subsalicylate, amoxicillin, metronidazole and omeprazole were prescribed respectively, and 4 weeks after treatment, in order to evaluate H. pylori eradication, urea breath test was done in all patients. The outcome of the study was the preference usage of licorice as an effective medication for H. pylori eradication. Results: Mean age of the patients in the control and case groups were 40.8 {\textpm} 15.5 and 42.2 {\textpm} 15.8 years, respectively (P = 0.726). Seventeen (56.7\%) patients in control group and 16 (53.3\%) in the case group were female (P = 0.795). Both groups were similar based on frequency of gastric or duodenal ulcer. Response to treatment were seen in 20 (67\%) and 17 (57\%) patients of case and control groups, respectively (P \> 0.05). Conclusion: Our study showed that licorice is as effective as bismuth in H. pylori eradication; therefore, in patients whom bismuth is contraindicated, licorice can be used safely instead.

}, keywords = {Bismuth, Helicobacter pylori eradication, Licorice}, doi = {10.4103/0974-8490.138289}, author = {Ali Momeni and Ghorbanali Rahimian and Abass Kiasi and Masoud Amiri and Soleiman Kheiri} }