@article {651, title = {Effects of Cinnamomum zeylanicum (Ceylon cinnamon) on blood glucose and lipids in a diabetic and healthy rat model}, journal = {Pharmacognosy Research}, volume = {4}, year = {2012}, month = {april,2012}, pages = {73-79}, type = {Original Article}, chapter = {73}, abstract = {

Objectives: To evaluate short- and long-term effects of Cinnamomum zeylanicum on food consumption, body weight, glycemic control, and lipids in healthy and diabetes-induced rats. Materials and Methods: The study was conducted in two phases (Phase I and Phase II), using Sprague-Dawley rats in four groups. Phase I evaluated acute effects on fasting blood glucose (FBG) (Groups 1 and 2) and on post-oral glucose (Groups 3 and 4) blood glucose. Groups 1 and 3 received distilled-water and Groups 2 and 4 received cinnamon-extracts. Phase II evaluated effects on food consumption, body weight, blood glucose, and lipids over 1 month. Group A (n = 8, distilled-water) and Group B (n = 8, cinnamon-extracts) were healthy rats, while Group C (n = 5, distilled-water) and Group D (n = 5, cinnamon-extracts) were diabetes-induced rats. Serum lipid profile and HbA1c were measured on D-0 and D-30. FBG, 2-h post-prandial blood glucose, body weight, and food consumption were measured on every fifth day. Results: Phase I: There was no significant difference in serial blood glucose values in cinnamon-treated group from time 0 (P \> 0.05). Following oral glucose, the cinnamon group demonstrated a faster decline in blood glucose compared to controls (P \< 0.05). Phase II: Between D0 and D30, the difference in food consumption was shown only in diabetes-induced rats (P \< 0.001). Similarly, the significant difference following cinnamon-extracts in FBG and 2-h post-prandial blood glucose from D0 to D30 was shown only in diabetes-induced rats. In cinnamon-extracts administered groups, total and LDL cholesterol levels were lower on D30 in both healthy and diabetes-induced animals (P \< 0.001). Conclusions: C. zeylanicum lowered blood glucose, reduced food intake, and improved lipid parameters in diabetes-induced rats.

}, keywords = {Blood glucose, Ceylon cinnamon, Cinnamomum zeylanicum, Diabetes mellitus, Lipids, Sprague-Dawley rats}, doi = {10.4103/0974-8490.94719}, author = {Priyanga Ranasinghe and Sanja Perera and Mangala Gunatilake and Eranga Abeywardene and Nuwan Gunapala and Sirimal Premakumara and Kamal Perera and Dilani Lokuhetty and Prasad Katulanda} } @article {835, title = {Lipid Constituents from Cissus quadrangularis Leaves}, journal = {Pharmacognosy Research}, volume = {1}, year = {2009}, month = {January 2010 }, pages = {231-233}, type = {Original Article}, chapter = {231}, abstract = {

A phytochemical investigation of Cissus quadrangularis leaves yielded five additional known compounds including eicosyl eicosanoate, tetratriacontanol, tetratriacontanoic acid, α-amyrin and β-sitosterol. The characterization of isolated compounds was achieved by chemical and spectral studies (IR, 1H NMR and Mass Spectroscopy).

}, keywords = {Cissus quadrangularis, Lipids, Vitaceae}, doi = {Nil}, author = {Jain Vandana and Thakur Achal and Hingorani Lal and Laddha KS} }