@article {1430, title = {Natural Marine Species Bioactive Compounds and their Ethnopharmacological Approach from Ecological Biodiversity: Sustainable Therapeutic Properties}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {June 2025}, pages = {697-706}, type = {Review Article}, chapter = {697}, abstract = {

Marine ecosystems are a rich source of bioactive compounds, offering immense potential for therapeutic applications. Research studies from pubmed, Google scholar, Science direct, databases provided derived from diverse organisms such as algae, sponges, mollusks, and marine microorganisms, these natural products exhibit a wide range of pharmacological properties, including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities. Ethnopharmacological knowledge, deeply rooted in traditional practices, serves as a valuable guide for identifying the medicinal potential of marine resources, creating a bridge between traditional wisdom and modern drug discovery. Recent advancements in biotechnological tools and sustainable bioprospecting have accelerated the discovery, isolation, and development of these bioactive compounds into promising therapeutic agents. Despite these advancements, significant challenges remain. The exploration of marine biodiversity is still limited, with many ecosystems, such as deep-sea and polar regions, largely unexplored. Sustainable harvesting practices, understanding the mechanisms of action and pharmacokinetics of marine bioactive, and mitigating the environmental impacts of large-scale extraction are critical issues. Additionally, the integration of ethnopharmacological knowledge with modern scientific approaches requires systematic validation and documentation. This review emphasizes the therapeutic potential of marine bioactive compounds, highlights the importance of sustainable and ethical bioprospecting practices, and identifies key research gaps that must be addressed to fully harness the benefits of marine biodiversity for global health.

}, keywords = {Biodiversity, Ethnopharmacology, Marine drugs, Marine organism, Marine Pharmacognosy, Secondary metabolites}, doi = {10.5530/pres.20252162}, author = {Paramita Ganguly and Puja Saha and Sandip Chatterjee and Prangya Paramita Pati} } @article {640, title = {Isolation and Identification of Bacterial Endophytes from Pharmaceutical Agarwood-producing Aquilaria Species}, journal = {Pharmacognosy Research}, volume = {5}, year = {2013}, month = {April 2013}, pages = {134-137}, type = {Short Communication }, chapter = {134}, abstract = {

Background:\ Resins and gums are used in traditional medicine and do have potential applications in pharmacy and medicine. Agarwood is the fragrant resinous wood, which is an important commodity from\ Aquilaria\ species and has been used as a sedative, analgesic, and digestive in traditional medicine. Endophytic bacteria are potentially important in producing pharmaceutical compounds found in the plants. Hence, it was important to understand which types of endophytic bacteria are associated with pharmaceutical agarwood-producing\ Aquilaria\ species.\ Objective:\ This study was undertaken to isolate and identify endophytic bacteria associated with agarwood-producing seven (7)\ Aquilaria\ species from Malaysia.\ Materials and Methods:\ Botanical samples of seven\ Aquilaria\ species were collected, and endophytic bacteria were isolated from surface-sterilized-tissue samples. The 16S rRNA gene fragments were amplified using PCR method, and endophytic bacterial isolates (EBIs) were identified based on 16S rRNA gene sequence similarity based method.\ Results:\ Culturable, 77 EBIs were analyzed, and results of 16S rRNA gene sequences analysis suggest that 18 different types of endophytic bacteria are associated with (seven)\ Aquilaria\ species. From 77 EBIs, majority (36.4\%) of the isolates were of\ Bacillus pumilus.\ Conclusion:\ These findings indicate that agarwood-producing\ Aquilaria\ species are harboring 18 different types of culturable endophytic bacteria.

}, keywords = {16S rRNA, Biodiversity, Endophytes, Malaysia, Medicine, Natural Products, Ribosomal DNA, Traditional medicine}, doi = {10.4103/0974-8490.110545 }, author = {Subhash J Bhore and Jagadesan Preveena and Kodi I Kandasamy} }