@article {1165, title = {Pharmaceutico-Analytical Assessment of Jeevanthyadi ghrita-A Polyherbal Ayurveda Formulation and its Potential Benefits}, journal = {Pharmacognosy Research}, volume = {15}, year = {2023}, month = {June 2023}, pages = {591-600}, type = {Original Article}, chapter = {591}, abstract = {

Background: Standardization and documentation of Traditional medicines have caught pace in recent past and yet remain a subject of discussion. Jeevanthyadi ghrita is a commonly prescribed empirically for debilitating health conditions. However, its pharmaceutical and analytical data remains untraced. Hence an attempt was made to prepare, screen the active biological constituents and review the recent activities of ingredients of the Jeevanthyadi ghirta to rationalize the classical indications. Results: Prepared Jeevanthyadi ghrita showed presence of Alkaloids and terpenoids. HPTLC analysis detected the presence of 7 and 11 active biological constituents at 254 nm and 366 nm respectively, which remains to be identified. No significant difference was noted between plain ghrita and prepared Jeevanthyadi ghrita in relation to AGMARK parameters. Conclusion: Recent activities of ingredients showed strong anti-inflammatory and immunomodulatory effect that has a relation to ceasing the pathology of debilitation.

}, keywords = {Alkaloids, Anti-inflammatory, Debilitation, Immunomodulatory, Jeevanthyadi ghrita, Pharmaceutico-Analytical}, doi = {10.5530/pres.15.3.062}, author = {Santosh F Patil and Suhaskumar Shetty and Purnachandra T} } @article {1057, title = {Ayurveda: The Prominence of Herbal Medicine in Containment of COVID-19}, journal = {Pharmacognosy Research}, volume = {14}, year = {2022}, month = {July 2022}, pages = {233-240}, type = {Review Article}, chapter = {233}, abstract = {

The global community is in a vulnerable and intricate state due to the COVID-19 pandemic given the lack of targeted drugs and extreme population making it an arduous journey to the public system of health care towards the extermination of the disease. The essentiality of newer compounds, novel medical instruments, and practices for diagnosis, cure, and prevention of the COVID-19 infection is the greatest concern. Since the persistent waves of COVID-19 are being observed at a variety of location across the globe, and the intensity and mutation of the virus is still possessing an inviolable threat to humanity. Along with conventional medicine, the application of traditional medicine practices using natural and herbal products has been proved effective in several disease conditions. The usage of Traditional Chinese medicine and ayurvedic medicine is used to treat COVID-19 infected patients in China and India respectively marks the contribution and effectiveness of traditional medical therapy in the restriction of the virus. The prominence of herbal products for prophylactic and symptomatic treatment for COVID-19 is notable and recommended by various organizations and governments in the world. All the pragmatic considerations and evidence to use ayurvedic practices on a large scale require further animal and robust human studies. This article reviews various practices, herbal products, effectiveness, case studies and the contribution of ayurvedic medicine, to be used to treat and restrict the viral epidemic and may further provide a forward insight into future learning, evidence compiling, and research in the respective domain.

}, keywords = {Antiviral, Ayurveda, COVID-19, Immunomodulatory, Inflammation}, doi = {10.5530/pres.14.3.33}, author = {Sarasa Meenakshi and V Udaya Kumar and Reny Sara Raju and Sameer Dhingra and Nitesh Kumar and V Ravichandiran and Krishna Murti} } @article {390, title = {Antioxidant and Immunomodulatory Activity of Hydroalcoholic Extract and its Fractions of Leaves of Ficus benghalensis Linn.}, journal = {Pharmacognosy Research}, volume = {8}, year = {2016}, month = {December 2015}, pages = {50-55}, type = {Original Article}, chapter = {50}, abstract = {

Background: Ficus benghalensis is a folk medicine indigenous plant of India. Several studies on this plant reported and focused on the biological profile of the plant. Objectives: This study is aimed to evaluate the antioxidant and immunomodulatory activity of F. benghalensis leaf extract using various in vitro screening methods of both parameters. Materials and Methods: Hydroalcoholic (FB1) extract and it{\textquoteright}s four fractions viz. n-hexane (FB2), n-butanol (FB3), chloroform (FB4), and water (FB5) of leaves of F. benghalensis investigated for their free radical scavenging activity using 1-1-diphneyl-2-picrylhydrazyl and 2, 2{\textquoteright}-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) radicals. A dose-response curve was plotted and IC50 values were determined to assess antioxidant activity. Nitroblue tetrazolium test, phagocytosis of killed Candida albicans and candidacidal assay were carried out to assess the immunomodulatory activity. Positive non-lymphoid cell number, mean particle number of killed C. albicans, percent value of killed C. albicans by neutrophils were calculated and presented. Results: All extracts showed antioxidant and prominent immunomodulatory activity with compared to standard. Conclusions: Hydroalcoholic (FB1) extract and its four fractions viz. n-hexane (FB2), n-butanol (FB3), chloroform (FB4), and water (FB5) showed promising antioxidant and immunomodulatory activity.

}, keywords = {Antioxidant, Candida albicans, Ficus benghalensis, Free radicals, Immunomodulatory}, doi = {10.4103/0974-8490.171107}, author = {Anil Subhash Bhanwase and Kallanagouda Ramappa Alagawadi} }