@article {1088, title = {Awareness of Natural Herbs{\textquoteright} Effect on Blood Pressure among the Western Region of Saudi Arabia Population: A Cross-Sectional Study}, journal = {Pharmacognosy Research}, volume = {14}, year = {2022}, month = {October 2022}, pages = {461-467}, type = {Original Article}, chapter = {461}, abstract = {

Background: Knowledge of potential interaction between herb-drug is essential to reduce both the risk of serious medical disorders such as life-threatening arrhythmia and uncontrolled blood pressure and the increased healthcare cost, because of treating these complications. Therefore, the primary aim of this study was to assess the western Saudi population{\textquoteright}s knowledge of potential interaction between herbal preparations containing Garlic, Ginger, Cinnamon, or Liquorice when concurrently administered with conventional hypotensive therapy. The secondary aim was to explore the source of information about herbal medicine use. Materials and Methods: A cross-sectional survey was conducted from January 2021 to February 2021 and involved Saudi Arabia{\textquoteright}s population from the western region. The study involved 164 participants by stratified random sampling. Results: The commonly used herbs among the western Saudi population included Garlic (44\%), Ginger (23\%), Cinnamon (13\%), Liquorice (3\%), and others (13\%). Approximately 45.1\% of herb user was based on advice from friends or relatives, 38.4\% were based on online information, and 16.5\% were based on medical resources. Our study showed that 70.7\% of the herb users weren{\textquoteright}t asked by their physicians about using herbal medicine, also 86.6\%\% weren{\textquoteright}t asked by their pharmacists. Conclusion: The study showed a low percentage of awareness of the potential effect of herbal medicines on blood pressure, and their potential interaction with conventional therapies. The study highlighted the low percentage of healthcare providers, who ask their patients about herbal medicine use before prescribing any new medication.

}, keywords = {Cinnamon, Drug interaction, Garlic, Ginger, Herbal medicine, Hypertension, Knowledge, Liquorice, Pharmacist, Physician}, doi = {10.5530/pres.14.4.67}, author = {Afnan Bahha and Aeshah Habib and Awsaf Alluqmani and Afnan Alqurashi and Ahlam Alotaibi and Yosra Al-Hindi and Arwa Fairaq} } @article {339, title = {Comparing the Effect of Rose Drop, Ginger, and Cinnamon on Sexual Function in Depressed Women with Sexual Dysfunction}, journal = {Pharmacognosy Research}, volume = {10}, year = {2018}, month = {July 2018}, pages = {314-318}, type = {Original Article}, chapter = {314}, abstract = {

Background: Sexual dysfunction is caused by multiple anatomical, physiological, medical, and psychological factors. Many studies have shown the efficacy of herbal remedies on increasing libido and sexual function. This study aimed to evaluate and compare the effects of three herbs of ginger, cinnamon, and rose on sexual function of depressed women with low sex drive. Materials and Methods: This randomized double-blinded clinical trial was conducted on 140 depressed women with sexual dysfunction who were divided into four groups receiving oral drops of rose, ginger, cinnamon, or placebo. The information about the two variables of sexual function and depression were collected by Female Sexual Function inventory questionnaire and Beck Depression Inventory, respectively. Data were analyzed using Chi-square, Wilcoxon signed-rank test, Kruskal{\textendash}Wallis test, and Pearson correlation coefficient. Results: The mean scores of sexual dysfunction and depression were significantly improved in the three groups after treatment (P \< 0.05) so that sexual dysfunction score in placebo group had the lowest rate of improvement with the mean of 1.55 {\textpm} 0.44 and in ginger group had the highest improvement rate with the mean of 4.04 {\textpm} 1.07. Depression in placebo group had the lowest improvement rate with the mean of 3.71 {\textpm} 1.94 and in cinnamon group had the highest rate of improvement with the mean of 6.29 {\textpm} 1.57, but there was no significant difference between the four groups (P \> 0.05). The factors such as received treatments with impact factor of 0.723 and age with impact factor of 0.170 had direct relation and depression with impact factor of -0.078 had reverse relation to sexual performance improvement (P \< 0.05). Conclusion: Herbal medicines, except for their positive impacts on sexual function, may have positive but minor effects on depression.

}, keywords = {Cinnamon, Depression, Ginger, rose, Sexual desire}, doi = {10.4103/pr.pr_150_17}, author = {Sheida Shabanian and Mahtab Ebrahimbabaei and Parvin Safavi and Masoud Lotfizadeh} } @article {650, title = {Antihyperlipidemic Effects of Ginger Extracts in Alloxan-induced Diabetes and Propylthiouracil-induced Hypothyroidism in (rats)}, journal = {Pharmacognosy Research}, volume = {5}, year = {2013}, month = {May 2013}, pages = { 157-161}, type = {Original Article }, chapter = {157}, abstract = {

Background:\ Diabetic mellitus and hypothyroidism lead to serum lipoproteins disorders. This study aims to investigate the potential effect of fresh ginger extracts\ Zingiber officinale\ roscoe (Family:\ Zingebiraceae) on serum lipid profile and on blood glucose in alloxan-induced diabetes and propylthiouracil-induced hypothyroidism in rats. Rats were divided into 11 groups: The normal G1, diabetic control rats G2, ginger 500 mg/kg treated diabetic rats G3, 10 mg/day atorvastatine-treated diabetic rats G4, [5 mg/day atorvastatine combined with 500 mg/kg ginger] treated diabetic rats G5, glibenclamid-treated diabetic rats G6, hypothyoidism control rats G7, 300 mg/kg ginger-treated hypothyroidism rats G8, 500 mg/kg ginger-treated hypothyroidism rats G9, 10 mg/day atorvastatine-treated hypothyroidism rats G10, [atorvastatine combined with 500 mg/kg ginger]treated hypothyroidism rats G11. Thirty days after treatment, samples were collected, to compare treated groups with normal and control groups, using Mann-Whitney U test\ P\ \< 0.01.\ Results\ : It revealed a decrease in the levels of total cholesterol (TC), and low density lipoprotein (LDL) in the serum of rats that were treated by ginger extracts, compared with the control groups. Previous extracts were also able to cause reduction in LDL to similar levels compared to normal group and that was the same effect of atorvastatin 10 mg/day. Combined effect was clear between the act of ginger at a dose of 500 mg/kg and atorvastatin; that levels of both TC and LDL in animals which received [atorvastatin 5 mg/day combined with ginger extract] was almost equal to levels in animals that received atorvastatin 10mg/day. Clear reduce in triglyceride, and clear increase in high density liopprotein were also recorded in the ginger-treated groups. Ginger was more active in hypothyroidism rats than in diabetic rats in reducing LDL and TC. Glucose levels were substantially reduced in ginger- treated diabetic groups.

}, keywords = {Alloxan-induced Diabetes, Atorvastatin, Ginger, Glibenclamide, Lipoproteins}, doi = {10.4103/0974-8490.112419 }, author = {Ahmad Sameer Al-Noory and Abdul-Nasser Amreen and Shatha Hymoor} }