@article {1398,
	title = {Exploring the Role of Phytoconstituents for Endocrine Disorder: A Review},
	journal = {Pharmacognosy Research},
	volume = {17},
	year = {2025},
	month = {April 2025},
	pages = {402-410},
	type = {Review Article },
	chapter = {402},
	abstract = {<p class="rtejustify">The endocrine system consists of various glands responsible for secreting hormones that regulate metabolism, growth, reproduction, and other physiological processes. Disruptions in this system, termed endocrine disorders, are linked to numerous health issues, such as obesity, diabetes, cardiovascular diseases, and metabolic syndromes. Moreover, the significance of factors such as life stage, gender and dietary habits in influencing health risks associated with endocrine disruption cannot be overstated. Synthetic medications for these conditions often have adverse side effects like hypoglycemia and heart complications, highlighting the need for alternative treatments. Herbal and natural remedies have shown promise in managing these disorders due to their lower toxicity and minimal side effects. Phytochemicals and poly-herbal therapies are emerging as effective strategies for addressing endocrine and metabolic disorders, influencing molecular targets like AMP-Activated Protein Kinase (AMPK) and Nuclear factor erythroid-2- related factor (Nrf2). Specific disorders such as diabetes, Addison{\textquoteright}s disease, and hyperthyroidism are characterized by hormone imbalances, with molecular mechanisms involving insulin resistance, cortisol dysregulation, and thyroid dysfunction. Additionally, the role of factors such as life stage, gender, and dietary habits in modulating endocrine disruption-associated health risks is crucial. Natural products, including flavonoids, catechins, resveratrol, and terpenes, are being explored for their therapeutic potential in regulating hormone levels and improving metabolic health.</p>
},
	keywords = {AMPK, Cardiovascular diseases, Diabetes, Endocrine system, Herbal medicine, Hormone imbalance, Metabolic disorders, Natural Products, Obesity, Phytochemicals},
	doi = {10.5530/pres.20252070},
	author = {Shweta Bhandari and Rahul Trivedi and Vishal Garg and Ajay Saini and Manish Gupta and Ram Singh}
}
@article {1326,
	title = {Unlocking the Therapeutic Potential of Terpenoids: A Roadmap for Future Medicine},
	journal = {Pharmacognosy Research},
	volume = {16},
	year = {2024},
	month = {October 2024},
	pages = {698-705},
	type = {Review Article},
	chapter = {698},
	abstract = {<p class="rtejustify">The naturally produced plant-derived compounds, known as phytochemicals, are biologically effective and incorporated to reduce the risk of numerous human illnesses. The utilization of phytochemicals for traditional medicine or functional nutrition has likely existed for as long as human history itself. Plants may gather phytochemicals in a variety of sections, including the roots, seeds as well as leaves and fruits. Among all the phytochemicals class, terpenoids are renowned for its proven biological activities and found in enormous capacity in medicinal plants. Several studies report the use of terpenoids in a wide range of diseases and infections. Different classes of terpenoids showed a variety of biological activities in chronic disorders and autoimmune diseases such as hypertension, diabetes, arthritis and cancer. These classes of compounds are also used against cancer and infectious diseases. In the present study we mainly highlight the use of terpenoids in different diseases and its availability in nature as different class. The role of terpenoids in developing new medications and enhancing current treatment methods is significant. However, thorough and detailed research is still warranted to entirely recognize the pharmacological effects of several terpenoids.</p>
},
	keywords = {Phytochemicals, Secondary metabolites, Terpenes, Terpenoids},
	doi = {10.5530/pres.16.4.81},
	author = {Sarika Sapan Parekh and Ghanshyam Ratilal Parmar and Divya Kanojiya and Sunil Bhaurao Baile and Rahul Trivedi and Foram Bhatt}
}
