@article {1266, title = {Identification of Bioactive Ingredients of Traditional Medicinal Plants Psiadia arabica Jaub. Tamarix articulata, Terminalia arjuna and Rhazya stricta by GC-MS in Saudi Arabia}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {570-573}, type = {Original Article}, chapter = {570}, abstract = {

Objectives: This study identified the main bioactive constituents extracted from a mixture containing four plant extracts. Four Saudi Traditional Medicinal plant extracts containing Psiadia arabica Jaub, Tamarix articulata, Terminalia arjuna and Rhazya stricta were identified using GC-Mass. Materials and Methods: The samples Psiadia arabica Jaub, Tamarix articulata, Terminalia arjuna and Rhazya stricta were collected from various regions of Saudi Arabia. The air-dried parts of each plant were powdered and soaked in methanol for 24 hr, except Psiadia arabica Jaub in chloroform. After that, it was obtaining the concentration plant extract through a rotary evaporator. The mixture of plant extracts was analyzed by GC-MS spectrometry. Results: The most abundant compounds identified including heneicosane (7.3\%), tetradecane 4,11-dimethyl- (7.11\%), Phytol (1.5\%), dodecane, 2,6,10-trimethyl- (1.9\%) and hexadecane (1.1\%), while the lowest concentrations were observed for 10-methylnonadecane, n-hexadecane, tridecane, 2-methyl-, Naphthalene, 1,2,4a,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)- and Dodecane, 2,6,11-trimethyl-. One of the main constituents noticed in the combination of four plants was heneicosane, which exhibits a strong antimicrobial effect. In addition, phytol showed multiple effects, including anti-inflammatory, antimicrobial, ant nociceptive, anxiolytic, metabolism-modulating and immune-modulating. Conclusion: These functional molecules identified are known to have different biological activities as antioxidant, antimicrobial, anti-proliferative and antidiabetic. Further studies needed to investigate the mechanism of action through signaling pathway in vivo and in vitro study.

}, keywords = {Bioactive ingredients, GC-MS Analysis, Psiadia arabica Jaub, Rhazya stricta, Saudi Arabia, Tamarix articulata, Terminalia arjuna, Traditional medicinal plants}, doi = {10.5530/pres.16.3.67}, author = {Taha A. Kumosani and Abeer Alnefayee and Elie Barbour and Mohammed Qari and Tarek Ahmed and Said Salama Moselh} }