@article {1404, title = {Advancements in Quantitative and Qualitative Methods for Quality Control of Herbal Drugs: A Comprehensive Review}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {April 2025}, pages = {411-415}, type = {Review Article}, chapter = {411}, abstract = {

The quality control of herbal drugs is a critical aspect of ensuring their safety, efficacy and reliability. The complex composition of herbal products, influenced by environmental, genetic and processing factors, necessitates robust analytical approaches. This review highlights recent advancements (2020-2024) in quantitative and qualitative methods for herbal drug quality control. Quantitative methods, such as HPLC, GC, and NMR spectroscopy, focus on the precise measurement of bioactive compounds, ensuring batch-to-batch consistency. Complementary to these are qualitative methods, including DNA barcoding, TLC and phytochemical screening, which authenticate botanical sources and detect adulterants. The integration of these methodologies provides a comprehensive framework for quality assessment, addressing both compositional consistency and authenticity. Despite advancements, challenges such as variability in raw materials and the lack of universal standards persist. This review underscores the need for interdisciplinary collaboration to overcome these challenges and standardize quality control practices globally. By leveraging recent technological innovations, the pharmaceutical industry and regulatory bodies can ensure the safety and efficacy of herbal medicines, fostering consumer confidence and adherence to regulatory requirements.

}, keywords = {Bioactive compounds, Chromatographic techniques, DNA Barcoding, Herbal, Plants, Qualitative, Quality control, Quantitative, Regulatory Standards, Spectrometry}, doi = {10.5530/pres.20252077}, author = {Seema Devi} } @article {1440, title = {Pharmacological Investigation of Actinidia deliciosa Extract in NSAIDs Induced Gastric Ulcer in Rodent Model}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {June 2025}, pages = {801-815}, type = {Review Article}, chapter = {801}, abstract = {

NSAIDs or non opoidal agents are commonly employed to treat rubor, dolor, relieve pain, but they often cause Gastrointestinal (GI) side effects, including gastritis, ulceration and bleeding. Natural products have emerged as potential alternatives or adjuncts to conventional treatments. The purpose of this study is to look at how Actinidia deliciosa (kiwi) extract protects against gastric ulcer brought on by NSAIDs. Background: NSAIDs are a group of pharmaceutical medications that are usually employed to treat rubor and dolor along with pyrexia as well as give a certain analgesic action at a certain therapeutic dose. At certain doses it is also used treat some sort of discomfort. While effective for these purposes, NSAIDs can also cause significant Gastrointestinal (GI) side effects, leading to conditions like gastritis, ulcers and even bleeding. This condition is known as NSAIDs-induced gastric ulcer. Materials and Methods: Rats will be divided into control, NSAIDs-induced gastric ulcer and NSAIDs-induced gastric ulcer treated with Actinidia deliciosa extract groups. The NSAIDs-induced gastric ulcer model will be established using indomethacin. The extract will be administered orally at various doses for a specified duration. GI damage will be assessed by measuring ulcer index, histological examination and biochemical markers (e.g., myeloperoxidase, malondialdehyde). The antioxidant activity of the extract will also be evaluated. Results: Preliminary findings suggest that Actinidia deliciosa extract significantly reduces NSAIDs-induced GI damage. It may exert its protective effects through antioxidant properties, inhibition of inflammatory mediators and mucosal barrier enhancement. Conclusion: Actinidia deliciosa extract shows promise as a potential natural agent for preventing NSAIDs-induced gastric ulcer. Further studies are warranted to elucidate the underlying mechanisms, determine the optimal dosage and administration route.

}, keywords = {Actinidia deliciosa, Antioxidant, Diclofenac, Gastric ulcer, Gastric ulcers, NSAIDs}, doi = {10.5530/pres.20252087}, author = {Arijit Chaudhuri and Arushi A and Manisha Dhiman and Anshul Thakur and Risha Kumari and Seema Devi and Shilpa Thakur and Ayusha A and Prince P and Nidhika N} } @article {1259, title = {LC-MS and HPTLC Profile of Crude Ethanol Extract of Plant Michelia champaca Linn.}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {490-494}, type = {Original Article}, chapter = {490}, abstract = {

Aim: The plant Michelia champaca L. plant is a very rich source of phytoconstituents with medicinal properties. The aim of the study is to analyze the chemical constituents present in the crude extract responsible for various pharmacological actions. Materials and Methods: The aerial parts of the plant Extracted with ethanol and subjected to LC-MS and HPTLC analysis by using Water Q-TOF micro coupled with 2795 HPLC and CAMAG TLC SCANNER -3. Results: LC-MS analysis showed the various peaks with low and high molecular weights indicating the presence of various phytochemicals. The compounds identified in the ethanol extract include parthenolides, quercetin, stigmasterol, sitosterol, and liriodenine and some unknown compounds by comparison with the SDBS database. HPTLC of the ethanol extract showed the Rf value of five compounds, were found to be more prominent. 0.15, 0.3, 0.45, 0.6, 0.75. identified by comparison with HPTLC - derived database. Conclusion: The compounds identified by LC-MS and HPTLC of the ethanol extract of the aerial plant Michelia champaca Linn. may be responsible for its various pharmacological activities, and hence this plant can be used in the treatment of various ailments.

}, keywords = {Chromatography, Extract, Plant, Spectroscopy}, doi = {10.5530/pres.16.3.59}, author = {Chander Mohan and Seema Devi} }