@article {1537, title = {Pharmacognostic Approach to the Green Synthesis and Pharmacological Evaluation of Copper Sulphide Nanoparticles Using Aqueous Extract of Catharanthus roseus Leaves}, journal = {Pharmacognosy Research}, volume = {18}, year = {2026}, month = {November 2025}, pages = {1-14}, type = {Original Article}, chapter = {1}, abstract = {

Background: Our study focused on the green synthesis of copper (II) complexes using the leaf extract of Catharanthus roseus. The phytochemical screening of the extract revealed the presence of flavonoids, tannins, glycosides, saponins, and alkaloids, which are believed to function as natural reducing, stabilizing, and capping agents in the synthesis process. These copper complexes were intended for use in antimicrobial dusting powders for wound healing applications. Materials and Methods: Multiple techniques were used to analyze the biosynthesized copper (II) complexes, including X-ray Diffraction (XRD), ultraviolet-visible (UV-vis) spectroscopy, Fourier-Transform Infrared Spectroscopy (FTIR), and Differential Scanning Calorimetry (DSC). Results showed that the average size of the particles was 3.4 nm. Surface plasmon resonance peaks were identified at 312 and 330 nm for the biosynthesized copper complex and at 393 and 369 nm for the pure plant extract. The synthesized copper complex and plant extract were incorporated into a dusting powder formulation. Several physicochemical characteristics of the powder were studied, including particle size, surface area, bulk density, tapped density, angle of repose, Carr{\textquoteright}s index, Hausner{\textquoteright}s ratio, and volume. The well diffusion technique was used to investigate the antibacterial effectiveness against Staphylococcus aureus and Escherichia coli. Plates inoculated with bacterial cultures were incubated at 37{\textordmasculine}C for 48 hr. Results: The copper complex remained stable over a six-month period, showing no agglomeration. The copper-enriched dusting powder demonstrated significant antibacterial activity, producing notable zones of inhibition compared to the plant extract formulation. The formulation displayed high permeability, rapid subcutaneous penetration, enhanced microcirculation, and accelerated histolytic tissue regeneration. Conclusion: The green-synthesized copper (II) complex derived from Catharanthus roseus exhibits promising antibacterial properties and enhanced wound healing potential. The copper-enriched dusting powder outperformed the pure plant extract formulation in antimicrobial activity and formulation characteristics, indicating its potential application in managing chronic wounds and preventing infections in medical and surgical contexts.

}, keywords = {Antimicrobial activity., Copper complex, Dusting powder, Green synthesis, Spectroscopic characterization}, doi = {10.5530/pres.20262371}, author = {Richa Kothari and Manoj Kumar Bajhaiya and Shubham Anand and Priya Thakur and Kanchan Thakur and Umesh Kushwaha and Ashish Goswami and Devendra Dhanorya} } @article {1510, title = {Phytochemical and Pharmacological Properties of Tinospora cordifolia (Giloy)}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {August 2025}, pages = {1171-1182}, type = {Review Article}, chapter = {1171}, abstract = {

Tinospora cordifolia (commonly known as Giloy or Guduchi) is a revered herb in traditional Ayurvedic medicine, widely recognized for its rejuvenating properties. The plant{\textquoteright}s therapeutic effects stem from a rich profile of phytochemicals-alkaloids, terpenoids, lactones, and polysaccharides-responsible for diverse pharmacological activities such as immunomodulation, antioxidant, anti-inflammatory, antidiabetic, antimicrobial, and hepatoprotective effects. This paper explores the phytochemical constituents, pharmacological potentials, and clinical relevance of T. cordifolia, with a focus on its mechanisms of action and its growing role in integrative medicine, particularly post-COVID-19. The review also highlights the necessity of more rigorous scientific studies and standardization to bridge traditional uses and modern therapeutic applications.

}, keywords = {Anti-inflammatory of Giloy, COVID-19 Adjunct Therapy, Giloy, Immunomodulatory Activity of Giloy, Pharmacological Properties of Giloy, Tinospora cordifolia}, doi = {10.5530/pres.20252350}, author = {Richa Kothari and Manoj Kumar Bajhaiya and Shefali Soni and Abhishek Kumar and Samreen Ali and Ankit Rajput and Prashant Kumar and Sagar Shrotriya and Kanchan Thakur} } @article {1413, title = {Unveiling the Phytochemical Profile and Therapeutic Benefits of Solanum xanthocarpum: A Systematic Review}, journal = {Pharmacognosy Research}, volume = {17}, year = {2025}, month = {April 2025}, pages = {440-451}, type = {Review Article}, chapter = {440}, abstract = {

Solanum xanthocarpum, a significant medicinal plant in traditional systems of medicine, possesses a rich phytochemical profile that contributes to its diverse therapeutic applications. This review explores the bioactive compounds such as alkaloids, flavonoids, and glycosides, which are responsible for the plant{\textquoteright}s pharmacological properties, including antioxidant, anti-inflammatory, antimicrobial, and antihyperglycemic activities. Recent studies have also highlighted its potential in treating respiratory disorders, liver dysfunction, and microbial infections. By consolidating traditional uses with modern pharmacological research, this paper aims to provide a comprehensive understanding of Solanum xanthocarpum, emphasizing its potential for future therapeutic developments.

}, keywords = {Anti-inflammatory effects, Anti-microbial activity, Antioxidant properties, Ethno-medicine of Solanum xanthocarpum, Phytochemical profile of Solanum xanthocarpum, Therapeutic benefits of Solanum xanthocarpum}, doi = {10.5530/pres.20252059}, author = {Nem Kumar Jain and Shubham Anand and Priyanka Kesari and Rekha Rani and Santosh Kumar and Akanksha Tiwari and Moti Lal and Devendra Dhanorya and Aman Sharma and Sakshi Singh and Manoj Kumar Bajhaiya} } @article {1257, title = {A Comprehensive Review of Ethnomedicinal, Phytochemical and Pharmacological Activity Profile of Achyranthes aspera}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {June 2024}, pages = {472-482}, type = {Review Article}, chapter = {472}, abstract = {

For centuries, humans have harnessed the healing properties of plants to address diverse health conditions. Ancient systems like Ayurveda and Unani medicine hold a rich repository of knowledge extolling the virtues of herbal remedies. Achyranthes aspera, one prolific native herbaceous plant in the South America, Asia and Africa often prospers as one common weed. Its many applications in traditional medicine for treating various diseases are at the heart of this global research. Achyranthes aspera is diverse many chemical ingredients, including terpenoids, alkaloids, steroids, saponins and flavonoids. This paper provides a thorough examination and elucidation of the phytochemical composition across different parts of Achyranthes aspera, delving into its traditional uses and expounding upon its pharmacological properties.

}, keywords = {Achyranthes aspera, Anti- microbial activity, anti-inflammatory activity, anti-oxidant, Antidiabetic activity}, doi = {10.5530/pres.16.3.57}, author = {Nem Kumar Jain and Shubham Anand and Priyanka Keshri and Santosh Kumar and Akshay Singh Sengar and Manoj Kumar Bajhaiya and Devendra Dhanorya and Sapna Yadav and Hema Katra and Sajal Mishra} } @article {1219, title = {A Comprehensive Review of Therapeutical and Ethnobotanical Aspects, Phytoconstituent and Pharmacological Activity of Aesculus indica}, journal = {Pharmacognosy Research}, volume = {16}, year = {2024}, month = {April 2024}, pages = {203-210}, type = {Review Article}, chapter = {203}, abstract = {

Aesculus indica Wall. Ex Camb. Hook, a member of the Hippocastanaceae family, exhibits robust growth in colder climates worldwide, showcasing its remarkable adaptability. Within its various components lie a diverse array of constituents, each harboring a treasury of advantageous compounds that have found utility across a spectrum of applications. These applications encompass the amelioration of gastrointestinal disturbances, facilitation of hemostasis, management of diabetes, and mitigation of various dermatological afflictions. Through a comprehensive synthesis of information gleaned from an array of authoritative sources including meticulous literature surveys, our study provides a thorough dissection. It traverses the multifaceted tapestry of this plant{\textquoteright}s applications, devlopes into its intricate chemical composition, and elucidates its nuanced effects on human health and well-being. This compendium stands as an invaluable reservoir, poised to aid and embolden scientists and researchers engaged in the exploration of natural products. Its content, meticulously aggregated and meticulously crafted, promises a resourceful springboard for their scholarly inquiries while assuring originality and authenticity in their pursuits.

}, keywords = {Aesculus indica, Anti-diabetic activite, Antimicrobial activity., Antioxidant, Pharmacognosy, Pharmacology activity, Phytochemistry}, doi = {10.5530/pres.16.2.26}, author = {Shubham Anand and Arijit Chaudhuri and Neha Chopra and Devendra Dhanorya and Manoj Kumar Bajhaiya and Gujjala Sai Sri Harsha and Vijeta Bhattacharya and Udichi Kataria and Gaurav Kumar} }