@article {62, title = {Phytochemical Screening and Gas Chromatography-Mass Spectrometry Analysis of Ethanol Extract of Scambiosa columbabria L.}, journal = {Pharmacognosy Research}, volume = {12}, year = {2020}, month = {February 2020}, pages = {35-39}, type = {Original Article}, chapter = {35}, abstract = {

Background: Scambiosa columbabria L. is commonly known as the wild scabious and is used in South Africa to treat various ailments such as wound bruises, painful menstruation, heartburn, and colic. Despite its extensive traditional usage, the bioactive constituents of this plant are yet to be explored. Objective: The present study was carried out to identify the bioactive constituents of the ethanol extract of S. columbabria by phytochemical screening and gas chromatography-mass spectrometry (GC-MS). Materials and Methods: Sixty grams of the powdered leaves was sequentially extracted by ethanol and later tested for preliminary phytochemical screening and further subjected to GC-MS analysis. Results: The results showed the presence of alkaloids, flavonoids, phenolics, tannins, steroids, terpenoids, and saponins in the extract. The GC-MS analysis revealed the presence of 16 major compounds, with flavonoids (40.84\%) being the most represented chemical class. Conclusion: The findings indicated that the plant possesses compounds with biological activities and therefore justifies its traditional usage in the treatment of skin and other diseases.

}, keywords = {Biological activity, Diseases, Gas chromatography-mass spectrometry, Phytochemical screening, Scambiosa columbabria}, doi = {10.4103/pr.pr_59_19}, author = {Idowu Jonas Sagbo and Ayuk Elizabeth Orock and Elizabeth Kola and Wilfred Otang-Mbeng} } @article {81, title = {Gas Chromatography{\textendash}Mass Spectrometry Analysis of the Volatile Compounds from the Ethanol Extracts of Bulbine asphodeloides and Helichrysum petiolare}, journal = {Pharmacognosy Research}, volume = {11}, year = {2019}, month = {August 2019}, pages = {219-223}, type = {Original Article}, chapter = {219}, abstract = {

Background: Bulbine asphodeloides and Helichrysum petiolare are important medicinal plants that commonly used in folklore medicine in South Africa for the management of skin ailments such as acne, burns, wounds, eczema, shingles, hives, psoriasis, sores, rosacea, and rashes. Despite their extensive use in traditional medicine, the chemical profiles of these medicinal plants have not been elucidated. Objective: The present study was carried out to identify and compare the gas chromatography{\textendash} mass spectrometry (GC{\textendash}MS) profiles of the volatile components from the ethanol extracts of both plants. Materials and Methods: The fresh leaves of both plants were collected from Alice, Eastern Cape, South Africa, and later oven dried and subjected for extraction and these extracts were further subjected to GC{\textendash}MS analysis using standard procedures. Results: The GC{\textendash}MS analysis revealed the presence of bioactive terpenes in the volatile components of the ethanol extracts of B. asphodeloides and H. petiolare. Conclusion: The findings reveal the presence of various bioactive compounds which therefore validates the therapeutic importance of these plants in the treatment of skin-related diseases.

}, keywords = {Bulbine asphodeloides, Gas chromatography{\textendash}mass spectrometry, Helichrysum petiolare, Phytochemicals, Skin ailments.}, doi = {10.4103/pr.pr_26_19}, author = {Wilfred Otang-Mbeng and Idowu Jonas Sagbo} }