@article {1119, title = {Effect of Saleekha and Majeeth in Polycystic Ovarian Disease: An Open Observational Study}, journal = {Pharmacognosy Research}, volume = {15}, year = {2023}, month = {December 2022}, pages = {168-175}, type = {Original Article}, chapter = {168}, abstract = {

Introduction: PCOD is a common, complex reproductive endocrinopathy characterized by menstrual irregularities, hyperandrogenism, polycystic ovaries, metabolic and psychological disorders and affects up to 18\% of reproductive-aged women. Objectives: To evaluate the effect of Saleekha and Majeeth in PCOD. Materials and Methods: Clinically diagnosed Patients (n=30) with PCOD in age 18-35 years with oligomenorrhea or amenorrhoea were included in the study. Patients with thyroid dysfunction, systemic diseases, endometrial tuberculosis, malignancies on hormonal treatment in the last 3 months, pregnancy, and lactation were excluded. The research drug was administered orally in a dose of 3.5 gm B.D safuf (powder) of Saleekha with Josh{\={a}}nda (decoction) of Majeeth 7 gm BD for 14 days/ cycle for three consecutive cycles. Outcome measures were changes in subjective parameters (nature of bleeding, duration of cycles, duration of flow, amount of flow, weight reduction) and objective parameters, pictorial blood loss assessment chart (PBAC) score, basal metabolic index (BMI), modified Ferriman Gallwey (mFG) score, acanthosis nigricans scale and pelvic ultrasonography. Data were analyzed using the paired Student t-test. Results: Marked improvement was observed in menstrual irregularity and PBAC score with p\<0.001 which is highly significant after the intervention. Significant change is seen in BMI, Ovarian volume, and SF-12 with p\<0.001 after treatment. Safety parameters were within the normal range. Interpretation and Conclusion: Research drugs (Saleekha and Majeeth) can be used as an alternate remedy in PCOD patients, as it significant effect to regularize menstruation by reduction of BMI and probably by improving insulin resistance in PCOD. No adverse effect of the research drug was noted during the trial.

}, keywords = {BMI, Majeeth, mFG, PBAC score, PCOD, Saleekha}, doi = {10.5530/097484900240}, author = {Shabnam Bano and Wajeeha Begum and Syeda Sumaiya} } @article {1096, title = {Effect of Althea officinalis Linnaeus (Tuqme khatmi) in Cervicitis (Iltehabe unqur rehm) - An Open Observational Clinical Study}, journal = {Pharmacognosy Research}, volume = {14}, year = {2022}, month = {October 2022}, pages = {454-460}, type = {Original Article}, chapter = {454}, abstract = {

Introduction: Cervicitis (Iltehabe unqur rehm) is characterized by inflammation of the cervix. Patients may present with complaints of abnormal vaginal discharge, post coital bleeding, dyspareunia, lower backache and lower abdominal pain. In Unani system of medicine Tukhme khatmi has been Discharge selected out from various available drugs in sailan ur raham. Aim: To evaluate the effect of Tukhme khatmi (Althea officinalis Linnaeus) in cervicitis. Materials and Methods: Clinically diagnosed patients (n=30) married women between age group of 18-45 yrs with regular menses were included considering selection criteria. Safuf of tukhme khitmi 5gms with Shahed and marham of tukhme khitmi will be prepared as per standard preparation. Safuf twice daily orally and Humul at bed time for 21 days after menses with weekly follow up. Subjective and objective parameters were assessed. Primary outcome and Secondary outcome were assessed for Improvement in Abnormal Vaginal LBA, LAP, CB, dyspareunia, VSS score, VAS and SF-12 for QOL and for any adverse effect safety profile was done. Results: there was a significant improvement in abnormal vaginal discharge with a mean of 2.37{\textpm}0.56 BT and 0.37{\textpm}0 AT with p\<0.0001 and other associated sign and symptoms of cervicitis. VSS with a mean of 1.80{\textpm}0.48 BT and 0.03{\textpm}0.182 AT shows significant change with p\<0.0001 after intervention. QOL was markedly improved. Conclusion: Considering the above result tuqme khitmi is effective in alleviating symptoms of cervicitis. It can serve as an alternative treatment without any side effects and it is also cost effective. Further research is needed in large sample size for longer duration.

}, keywords = {Cervicitis, Humul, SF-12, Tuqme khatmi, VAS, VSS, Warme unqur rehm}, doi = {10.5530/pres.14.4.66}, author = {S Shazamani and Wajeeha Begum and Syeda Sumaiya} }