@article {128, title = {Immunological, Biochemical, and Infant-Toddler Quality of Life Parameter-Based Study of Swarna Prashana (a Herbo-Mineral Ayurveda Preparation) in Infants}, journal = {Pharmacognosy Research}, volume = {13}, year = {2021}, month = {April 2021}, pages = {34-41}, type = {Original Article}, chapter = {34}, abstract = {

Background:\ Increasing rate of emergence of newer infection, resistance to antibiotics, reoccurrence of infections, and malnutrition have created a space for an effective and safe solution of above issues to mankind.\ Swana Prashana\ is a unique concept of Indian system of medicine for improving the generalized immunity consequently helping the child to resist and fight against various infection and diseases.\ Aims:\ Study was planned to evaluate the efficacy of Swarna Prashana and Swarna Vacha Prashana in infants.\ Materials and Methods:\ A randomized, controlled, single-blind clinical study was planned in healthy infants to study the effect of\ Swarna Prashana\ in anthropometry, hematological, biochemical, immunological, and infant-toddler quality of life (ITQOL) parameters in 3 differently categorized groups namely Group A: (n\ = 39,\ Ghrita and Madhu). Group B: (n\ = 42,\ Swarna Bhasma, Ghrita and Madhu) Group C: (n\ = 38,\ Swarna Bhasma, Ghrita, Madhu\ and\ Vacha Churna).\ Results:\ The present clinical study showed statistically highly significant (P\ \< 0.001) increase in all the anthropometrical measurements of infants all three groups. The drugs did not hamper normal growth of the infants and they did not have any additional effect on enhancing the anthropometrical values. Hematological and biological parameters did not show significant difference in comparison in all groups. The results of Renal function and liver function tests were in normal limits after completion of treatment and post treatment follow-up suggestive of safe to be administered in infants. Immunological parameters also did not show significant difference of comparison in all groups except in Group C where immunoglobulin G (IgG), IgM, albumin, globulin levels were increased. Group C significantly improved all the ITQOL parameters while on comparison significant difference was observed in improving the physical abilities only.\ Conclusion:\ Current study suggests\ Swarna Prashana\ as infants health promotive and morbidity preventive. Author advocates a large scale randomized double blind clinical trial for further validation of impact of\ Swarna Prashan\ as mass health-care initiative.

}, keywords = {Ayurveda, Immunomodulation, Swarnaprashan, Vyadhi kshamatva}, doi = {10.4103/pr.pr_69_20}, author = {Satyawati Rathia and Lowkesh Chandravanshi and Virendra Kumar Kori and Kalpana Patel and Prashant Kumar Gupta} }