@article {1208, title = {Pharmacognostic Standardization, Heavy Metal Analysis and Antioxidant Potential of Iris kashmiriana Baker Rhizome}, journal = {Pharmacognosy Research}, volume = {16}, year = {2023}, month = {December 2023}, pages = {123-131}, type = {Original Article}, chapter = {123}, abstract = {

Background: Iris kashmiriana Baker, often known as Mazarmond, is a plant species classified under the Iridaceae family. This specific botanical specimen has notable therapeutic properties and has been traditionally used for the treatment of many diseases. The rhizomes are considered to be a substantial repository of secondary metabolites and have been extensively investigated for their potential in many activities, including immunomodulation, anticancer capabilities, antibacterial effects, and anthelmintic qualities. Currently, there is a lack of study about the establishment of standardization methods for the plant. Aim: the purpose of this research was to conduct standardization, phytochemical analysis, heavy metal analysis, and assessment of the antioxidant capacity of the rhizomes of Iris kashmiriana Baker, a native plant found in the Kashmir valley. Materials and Methods: The botanical specimens were gathered, subjected to a process of air drying in a shaded environment, and afterwards ground into a fine powder. The techniques used for conducting pharmacognostic investigations and phytochemical screening were in compliance with the guidelines set out by the World Health Organization (WHO) and the Indian Pharmacopoeia. Results: Several distinct features were observed after the implementation of organoleptic, microscopic examination, standardization, and phytochemical analysis. The quantities of all heavy metals were found to be under the acceptable range set by the World Health Organization (WHO). Furthermore, the plant extracts demonstrated significant antioxidant activity. Conclusion: This research serves as a first endeavour in the process of standardizing Iris kashmiriana rhizomes, with the objective of creating a comprehensive profile of their attributes. The results obtained from this inquiry may be used as a valuable point of reference for taxonomic verification and quality control of the perennial plant. Furthermore, the use of standardized rhizomes may be investigated as a potential alternative in the field of medicine for addressing various ailments. This alternative approach presents a higher level of safety and a decreased likelihood of unpleasant responses.

}, keywords = {Antioxidant activity., Iris kashmiriana Baker, Phytochemical analysis, Standardization}, doi = {10.5530/pres.16.1.15}, author = {Saeema Farooq and Roohi Mohi-ud-din and Prince Ahad Mir and Reyaz Hassan Mir and Nishant Kumar and Zulfiqar Ali Bhat} } @article {115, title = {Pharmacognostical Standardization, Phytochemical Investigation, and Anthelminthic Activity of Arisaema propinquum Schott Rhizomes}, journal = {Pharmacognosy Research}, volume = {12}, year = {2020}, month = {May 2020}, pages = { 181-185}, type = {Original Article}, chapter = {181}, abstract = {

Ethnopharmacology: Arisaema propinquum Schott (Araceae) is commonly known as cobra lily. Traditionally, the rhizomes were used as vermifuge, in rheumatism, as stomachache, and in snake bites. Objectives: The present study was designed to evaluate the pharmacognostical parameters and anthelminthic activity of A. propinquum rhizomes. Materials and Methods: The rhizomes of A. propinquum Schott was collected, shade dried and then powdered, and then evaluated for pharmacognostic parameters such as macro- and microscopical characters, physico-chemical parameters, and phytochemical analysis using standard procedures. Anthelminthic activity of the extracts was elevated against Pheretima posthuma. Results: The rhizomes are light brown in color with pungent odor and astringent taste. Transverse section of rhizomes showed intercellular schizogenous cavities, xylem vessels, phloem vessels, and parenchymatous cells. Phytochemical screening of the extracts reveals the presence of alkaloids, carbohydrates, cardiac glycosides, coumarins, proteins, amino acids, phenols, tannins, flavonoids, saponins, steroids, and terpenoids. Physiochemical parameters including ash values showed 6.32\% total ash, 1.77\% acid insoluble ash, 5.15\% water-soluble ash, and 8.55\% sulfated ash. Other parameters such as extractive value, foreign matter, moisture content, swelling index, foaming index, pH of different solvents, and fluorescence analysis were also determined. Both the methanolic and aqueous extracts of A. propinquum showed dose-dependent anthelminthic activity against P. posthuma compared to standard albendazole. Conclusion: This is the first report on the pharmacognostic studies and anthelminthic activity of A. propinquum Schott. Data composed from such studies can be used as a standard in the quality control of this plant used as an herbal medicine for the treatment of various diseases.

}, keywords = {Anthelminthic, Arisaema propinquum, Pharmacognostical standardization, Pheretima posthuma, Phytochemical investigation}, doi = {10.4103/pr.pr_106_19}, author = {Prince Ahad Mir and Roohi Mohi-ud-din and Mohd Akbar Dar and Ghulam Nabi Bader} }