@article {702, title = {GC-MS Analysis of Bio-active Compounds in Methanolic Extract of Lactuca runcinata DC}, journal = {Pharmacognosy Research}, volume = {6}, year = {2014}, month = {December,2013}, pages = {58-61}, type = {Original Article}, chapter = {58}, abstract = {

Background: The presence of phytochemical constitutes has been reported from species of the Compositae (Asteraceae). Hitherto no reports exist on the phytochemical components and biological activity of Lactuca runcinata DC. Objective: The present study was designed to determine the bioactive compounds in the whole plant methanol extract of Lactuca runcinata. Materials and Methods: Phytochemical screening of the entire herb of Lactuca runcinata DC revealed the presence of some bio-active components. Gas chromatography-mass spectrometry (GC-MS) analysis of the whole plant methanol extract of Lactuca runcinata was performed on a GC-MS equipment (Thermo Scientific Co.) Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II. Results: The phytochemical tests showed the presence of alkaloids, cardiac glycosides, flavonoids, phenols, phlobatannin, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, and protein/amino acids in methanolic extract of L. runcinata. The GC-MS analysis has shown the presence of different phytochemical compounds in the methanolic extract of Lactuca runcinata. A total of 21 compounds were identified representing 84.49\% of total methanolic extract composition. Conclusion: From the results, it is evident that Lactuca runcinata contains various phytocomponents and is recommended as a plant of phytopharmaceutical importance.

}, keywords = {GC-MS Analysis, Lactuca runcinata, Phytochemical screening, Whole plant methanol extract}, doi = {10.4103/0974-8490.122919}, author = {Lakshmi Kanta Kanthal and Akalanka Dey and K Satyavathi and P Bhojaraju} }