@article {604, title = {Flavonoid Glycosides and Pharmacological Activity of Amphilophium Paniculatum}, journal = {Pharmacognosy Research}, volume = {5}, year = {2013}, month = {January 2013}, pages = {17-21}, type = {Original Article }, chapter = {17}, abstract = {

Background:\ Nothing is reported on\ Amphilophium paniculatum\ (L.) Kunth. This study aimed at investigation of chemical constituents of the leaves of\ Amphilophium paniculatum,\ grown in Egypt, in addition to pharmacological evaluation.\ Materials and Methods:\ Isolation of a new compound, along with 5 known flavonoids. Pharmacological activities were carried out on different extracts of\ A. paniculatum\ leaves.\ Results:\ Identification of a new flavone glycoside, acacetin 8-C-β-D- glucopyranosy l-(1{\textrightarrow}2)-α-L-rhamnopyranoside (1) in addition to 5 known flavonoids. The 70\% ethanol crud extract and its successive chloroform, ethyl acetate, and 100\% ethanol extracts showed significant anti-inflammatoryactivity,analgesic effect, antipyretic activity, antioxidant activity, and anti-hyperglycemic activity. Determination of the median lethal dose (LD\ 50\ ) revealed that the different extracts were safe.

}, keywords = {Amphilophium Paniculatum, Bignoniaceae, Flavonoids, Pharmacology}, doi = {10.4103/0974-8490.105643 }, author = {Mahmoud I Nassar and El-Sayed A Aboutabl and Dina M Eskander and Mary H Grace and Ezzel-Din A EL-Khrisy and Amany A Sleem} } @article {626, title = {Secondary Metabolites and Bioactivities of Albizia Anthelmintica}, journal = {Pharmacognosy Research}, volume = {5}, year = {2013}, month = {April 2013}, pages = {80-85}, type = {Original Article }, chapter = {80}, abstract = {

Background:Albizia\ species are rich in phenolics and terpenes in the different plant organs. They are widely used in traditional Chinese medicine. So this study investigated the phytochemical and biological activities of\ AlbiziaAnthelmintica.\ Materials and Methods:\ Column chromatography has been performed for the isolation of compounds. Bioactivity studies of\ A. anthelmintica\ leaves were carried out on aqueous ethanol extract and some pure compounds were tested for their antioxidant activities.\ Results:\ Eight compounds have been isolated for the first time from\ A. anthelmintica. The aqueous ethanol extract of\ A. anthelmintica\ showed moderate anti-inflammatory activity and significant for both analgesic and antioxidant activities. Quercetin-3-O-β-D-glucopyranoside, kaempferol-3-O-β-D-glucopyranoside, kaempferol-3-O-(6β-O-galloyl-β-D-glucopyranoside and quercetin-3-O-(6β-O-galloyl-β-D-glucopyranoside) exhibited potent antioxidant scavenging activity towards diphenyl-picrylhydrazine.

}, keywords = {Albizia anthelmintica, Analgesic, Antioxidant, Anti-inflammatory, Diphenyl-picrylhydrazine, Flavonoids}, doi = {10.4103/0974-8490.110530}, author = {Tahia K Mohamed and Mahmoud I Nassar and Ahmed H Gaara and Walaa A El-Kashak and I{\~n}aki Brouard and Sayed A El-Toumy} }