@article {545, title = {Antioxidant and Antiacetylcholinesterase Activity of Teucrium Hyrcanicum,}, journal = {Pharmacognosy Research}, volume = {7}, year = {2015}, month = {June 2015}, pages = {s15-s19}, type = {Original Article }, chapter = {s15}, abstract = {

Background:Teucrium hyrcanicum\ belonging to the Lamiaceae family is a native plant in Iran; it is called Maryam nokhodi-e-jangali in Farsi.\ Objective:\ The aim of this study is to evaluate acetylcholinesterase inhibition (AChEI), antioxidant activity and flavonoids content of\ T.hyrcanicum\ methanol extract.\ MaterialsandMethods:\ The air-dried and the ground aerial parts of\ T. hyrcanicum\ were extracted by percolation method with methanol. Antioxidant activity of the extract was investigated by using 2,2{\textquoteright}-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power assay (FRAP) methods. In addition, AChEI and flavonoid content of\ T. hyrcanicum\ methanol extract were measured.\ Results:\ The results showed that total flavonoid content of\ T. hyrcanicum\ in reference to the standard curve for quercetin was 20.70 {\textpm} 0.05 mg quercetin equivalents/g of extract. In the FRAP method, the antioxidant activity of\ T. hyrcanicum\ extract and butyl hydroxyanisole (BHA) (as a positive control) were 657.5 {\textpm} 0.04 and 880 {\textpm} 0.06 mmol Fe II/1 g dried extract. According to results of DPPH assay, half maximal inhibitory concentration (IC50\ ) value for DPPH radical-scavenging activities of\ T. hyrcanicum\ methanol extract, vitamin E and BHA were 74.6, 14.12 and 7.8 μg/mL, respectively. IC\ 50\ value for AChEI of\ T. hyrcanicum\ and donepezil as a positive control were 2.12 mg/mL and 0.013 mg/mL.\ Conclusion:\ The results of the present study showed\ T. hyrcanicum\ is a natural antioxidant that the flavonoid content can be responsible for extract effects.

}, keywords = {Aantioxidant Activity, Acetylcholinesterase Inhibitory, Flavonoid Contents, Teucrium Hyrcanicum}, doi = {10.4103/0974-8490.157993 }, author = {Fereshteh Golfakhrabadi and Fatemeh Yousefbeyk and Tahmineh Mirnezami and Pedram Laghaei and Mannan Hajimahmoodi and Mahnaz Khanavi} } @article {957, title = {Chemical Composition and Larvicidal Activity of Essential oil of Cupressus arizonica E.L. Greene Against Malaria Vector Anopheles Stephensi Liston (Diptera: Culicidae),}, journal = {Pharmacognosy Research}, volume = {3}, year = {2011}, pages = {135-139}, chapter = {135}, abstract = {

Background: Using botanical insecticides as an alternative biocontrol technique for vector control is considered by some scientists. Materials and Methods: Chemical composition of the essential oil was analyzed using gas chromatography{\textendash}mass spectrometry (GC{\textendash}MS). In addition, the mosquito larvicidal activity of leaf essential oil of Cupressus arizonica was investigated against fourth instar larvae of laboratory-reared An. stephensi according to the method of the World Health Organization. Results: Of 46 constituents in the oil, limonene (14.44\%), umbellulone (13.25\%) and α-pinene (11\%) were determined as the main constituents. Cupressus arizonica volatile oil showed significant larvicidal activity against An. stephensi with LC50 and LC90 values 79.30 ppm and 238.89 ppm respectively. Clear dose-response relationships were established with the highest dose of 160 ppm essential oil with almost 100\% mortality. Discussion: The results from this study revealed that C. arizonica essential oil could be considered as a natural larvicide against An. stephensi. However, the field evaluation of the formulation is necessary.

}, keywords = {Anopheles stephensi, Botanical insecticide, Cupressus arizonica, Essential oil, Iran, Vector control}, doi = {10.4103/0974-8490.81962}, author = {Mohammad Mehdi Sedaghat and Alireza Sanei Dehkordi and Mahnaz Khanavi and Mohammad Reza Abai and Fatemeh Mohtarami and Hassan Vatandoost} }