@article {316,
	title = {Honey and Health: A Review of Recent Clinical Research},
	journal = {Pharmacognosy Research},
	volume = {9},
	year = {2017},
	month = {April 2017},
	pages = {121-127},
	type = {Review Article},
	chapter = {121},
	abstract = {<p class="rtejustify">Honey is one of the most appreciated and valued natural products introduced to humankind since ancient times. Honey is used not only as a nutritional product but also in health described in traditional medicine and as an alternative treatment for clinical conditions ranging from wound healing to cancer treatment. The aim of this review is to emphasize the ability of honey and its multitude in medicinal aspects. Traditionally, honey is used in the treatment of eye diseases, bronchial asthma, throat infections, tuberculosis, thirst, hiccups, fatigue, dizziness, hepatitis, constipation, worm infestation, piles, eczema, healing of ulcers, and wounds and used as a nutritious supplement. The ingredients of honey have been reported to exert antioxidant, antimicrobial, anti-inflammatory, antiproliferative, anticancer, and antimetastatic effects. Many evidences suggest the use of honey in the control and treatment of wounds, diabetes mellitus, cancer, asthma, and also cardiovascular, neurological, and gastrointestinal diseases. Honey has a potential therapeutic role in the treatment of disease by phytochemical, anti-inflammatory, antimicrobial, and antioxidant properties. Flavonoids and polyphenols, which act as antioxidants, are two main bioactive molecules present in honey. According to modern scientific literature, honey may be useful and has protective effects for the treatment of various disease conditions such as diabetes mellitus, respiratory, gastrointestinal, cardiovascular, and nervous systems, even it is useful in cancer treatment because many types of antioxidant are present in honey. In conclusion, honey could be considered as a natural therapeutic agent for various medicinal purposes. Sufficient evidence exists recommending the use of honey in the management of disease conditions. Based on these facts, the use of honey in clinical wards is highly recommended.</p>
},
	keywords = {Antioxidant, Flavonoids, Honey, Polyphenols, Therapeutic agent, Traditional},
	doi = {10.4103/0974-8490.204647},
	author = {Saeed Samarghandian and Tahereh Farkhondeh and Fariborz Samini}
}
@article {708,
	title = {Anticarcinogenic Effect of Saffron (Crocus sativus L.) and its Ingredients},
	journal = {Pharmacognosy Research},
	volume = {6},
	year = {2014},
	month = {March,2014},
	pages = {99-107},
	type = {Review article},
	chapter = {99},
	abstract = {<p class="rtejustify">Conventional and newly emerging treatment procedures such as chemotherapy, catalytic therapy, photodynamic therapy and radiotherapy have not succeeded in reversing the outcome of cancer diseases to any drastic extent, which has led researchers to investigate alternative treatment options. The extensive repertoire of traditional medicinal knowledge systems from various parts of the world are being re-investigated for their healing properties Crocus sativus L., commonly known as saffron, is the raw material for one of the most expensive spice in the world, and it has been used in folk medicine for centuries . Chemical analysis has shown the presence of more than 150 components in saffron stigmas. The more powerful components of saffron are crocin, crocetin and safranal. Studies in animal models and with cultured human malignant cell lines have demonstrated antitumor and cancer preventive activities of saffron and its main ingredients, possible mechanisms for these activities are discussed. More direct evidence of anticancer effectiveness of saffron as chemo-preventive agent may come from trials that use actual reduction of cancer incidence as the primary endpoint. This review discusses recent literature data and our results on the cancer chemopreventive activities of saffron and its main ingredients.</p>
},
	keywords = {Anticarcinogenic effect, Its ingredients, Saffron},
	doi = {10.4103/0974-8490.128963},
	author = {Saeed Samarghandian and Abasalt Borji}
}
