@article {895, title = {Chemical Constituents and Bioactivities of Malabaila suaveolens}, journal = {Pharmacognosy Research}, volume = {1}, year = {2009}, month = {January 2010 }, pages = {342-347}, type = {Original Article}, chapter = {342}, abstract = {

Volatile oil components, fatty acids, β-amyrin, and sterols were identified in the n-hexane extract of Malabaila suaveolens Coss. fruits. Angelicin, 4,7,9-trimethyl psoralen, isopimpinellin and umbelliferone were isolated from the dichloromethane extract of the plant. 5-Hydroxy 7, 3{\textquoteleft}, 4{\textquoteleft}-trimethoxyflavone, apigenin and its 7-O-β-D-glucopyranoside were isolated from the ethyl acetate extract. From the methanol extract, a new flavonoid, apigenin 7-O-(6{\textquoteleft}{\textquoteleft}-O-p-hydroxybenzoyl)-β-D-glucopyranoside (1), along with vicenin 2, acacetin 7-O-rutinoside, and 6-hydroxyapigenin 7-O-β-D-glucopyranoside were isolated. Toxicity study of n-hexane, dichloromethane, ethyl acetate extract and methanolic extracts of the plant proved that it is relatively nontoxic. The tested extracts showed significant analgesic and anti-inflammatory effects as compared with control groups and reference drugs. Also, the tested extracts showed significant antioxidant activity as compared with reference.

}, keywords = {Bioactivity., Coumarins, Flavonoids, Malabaila suaveolens}, doi = {Nil}, author = {Nassar Mahmoud I and Aboutabl El-Sayed A and Maklad Yousreya A and El-Khrisy Ezzel-Din A and Osman Abeer F} }