@article {671, title = {In vitro H + -K + ATPase Inhibitory Potential of Methanolic Extract of Cissus Quadrangularis Linn.}, journal = {Pharmacognosy Research}, volume = {4}, year = {2012}, month = {april,2012}, pages = {123-126}, type = {Short Communication}, chapter = {123}, abstract = {

Objective: This study was undertaken to study in vitro H + -K + ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn. Materials and Methods: Total phenolic and flavonoid contents from extract was quantified and H + -K + ATPase inhibition assay was performed in presence of different concentrations of standard (omeprazole) and methanol extract. Results: Extract showed significant (*P \< 0.05) proton pump inhibitory activity in the goat gastric mucosal homogenate which was comparable to standard. Conclusions: These findings showed that methanolic extract of C. quadrangularis Linn. is potent inhibitor of proton pump.

}, keywords = {Cissus quadrangularis Linn., H+-K+ ATPase inhibition assay, in vitro.}, doi = {10.4103/0974-8490.94738}, author = {Priyanka Yadav and Aditya Ganeshpurkar and Gopal Rai} }