@article {593, title = {The Effects of Aqueous Extract of Cleistanthus Collinus (Roxb.) (Euphorbiaceae) Leaves On Rat Blood Pressure}, journal = {Pharmacognosy Research}, volume = {4}, year = {2012}, month = {July,2012}, pages = {178-180}, type = {letter te the editor}, chapter = {178}, abstract = {

The genus Cleistanthus (Euphorbiaceae) comprises about 140 species which includes Cleistanthus collinus, Cleistanthus patulus, Cleistanthus schlechteri, and Cleistanthus gracili.[1] Cleistanthus collinus (Roxb.) Benth. ex Hook. f. (Euphorbiaceae) is known as a toxic plant and found in Africa, India, Sri Lanka, and Malaysia.[2] In India, this plant is commonly used as a suicidal poison. All parts of the plant are reported to be toxic and used as suicidal, homicidal, cattle and fish poison and for inducing criminal abortion.[3] In patients, the clinical manifestations of C. collinus poisoning include hyperthermia, hypokalemia, ECG abnormalities (prolongation of QT interval, ST depression, and flat P wave), and elevation of hepatic enzymes such as alkaline phosphatase (ALP), serum glutamic pyruvic transaminase (SGPT), and serum glutamic oxaloacetic transaminase (SGOT).[2] In some clinical cases, a water decoction of C. collinus causes fall in blood pressure.[2] Hence, this study was planned to determine the effects of aqueous extract of C. collinus leaves on rat blood pressure using an invasive procedure. Read More ....

}, keywords = {Nil}, doi = {10.4103/0974-8490.99086}, author = {S Parasuraman and R Raveendran} }