@article {236, title = {In vitro Screening for Antioxidant and Antimicrobial Properties of Three Lebanese Medicinal Plants Crude Extracts}, journal = {Pharmacognosy Research}, volume = {11}, year = {2019}, month = {April 2019}, pages = {127-133}, type = {Original Article}, chapter = {127}, abstract = {

Background: Despite its small geographic area, Lebanon is characterized by a natural wealth in medicinal plants. Lebanese flora has about 2600 species, where \>100 are endemic and are used in traditional medicine for their therapeutic effects. Objective: To evaluate the antioxidant and antimicrobial activities of dichloromethane, methanol, and aqueous crude extracts of three Lebanese medicinal plants: Geranium robertianum, Asphodelus microcarpus, and Alcea setosa. Materials and Methods: The antioxidant activity of different crude extracts was determined using the free radical, 1,1-diphenyl-2-picrylhydrazyl. Antimicrobial activity was evaluated in a plate-hole diffusion assay against two Gram-negative (Pseudomonas aeruginosa and Escherichia coli) bacterial strains, one Gram-positive (Staphylococcus aureus) bacterial strain, and a fungal strain (Candida albicans). Results: Methanol and aqueous extracts of G. robertianum possessed high scavenging activity (Radical scavenging activity ( RSA) \>85\%) at 0.3 mg/mL followed by the extracts of A. microcarpus which showed a moderate activity. G. robertianum extracts exhibited good inhibition diameters against S. aureus growth. Conclusion: Obtained results give an overall view on the bioactivities of three Lebanese medicinal plants crude extracts.

}, keywords = {Alcea setosa, Antimicrobial activity, Antioxidant activity, Asphodelus microcarpus, Crude extracts, Geranium robertianum}, doi = {10.4103/pr.pr_171_18}, author = {Josiane Alhage and Hoda Elbitar} }