GC-MS Analysis of an Ayurveda Formulation Erandamula Niruha Basti (Medicated Therapeutic Enema)

Background: The scientific credibility of modern and Indian System of Medicine, such as Ayurveda and Siddha, is highly relevant in the current era. The gas chromatography-mass spectrometry (GC-MS) instrument separates chemical mixtures (the GC component) and identifies the components at a molecular level. Since Basti is the most effective remedy for Vata Dosha, it occupies a prominent position among the five Therapeutic measures of Panchakarma. Aim and Objectives: This study uses Gas Chromatography-Mass Spectrometry (GC-MS) analysis to examine the Erandamula Niruha Basti, with the goal of identifying links between its medicinal properties and the biomolecules it comprises. Materials and Methods: GCMS analysis was conducted using 7890 A GC with 5975C with a triple-axis detector. The compounds were identified after comparing the spectral configurations obtained with those of the available mass spectral database (NIST-08 SPECTRAL DATA). Results: Important compounds were found in the profile that resulted, showing the presence of some important molecules like 5-Acetoxymethyl- 2-furaldehyde,2,4-Dihydroxy-2,5-dimethyl-3(2H)-furan-3-one,3-Furanmethanol, and furfural, which exhibit pharmacological actions like anti-inflammatory and antioxidant, which is in keeping with the therapeutic qualities that Eranndamoola Niruha Basti is said to possess. Conclusion: The current study uses GC-MS analysis to demonstrate the scientific validity of conventional formulations such as Erandamoola Niruha Basti. This Ayurvedic remedy’s pharmacological claims are supported by the finding of important phytochemicals. Certain molecules, like furfural and 5-acetoxymethyl-2-furaldehyde, have antioxidant and anti-inflammatory qualities. These results are consistent with Basti’s traditional therapeutic benefits in treating Vata disorders. The discovery of these biomolecules validates Erandamula Niruha Basti’s function as a potent treatment for Vata vyadhi (musculoskeletal disorders) in Ayurveda.