ArticlesAbstractPharmacognosy Research,2025,17,2,452-461.DOI:10.5530/pres.20252085Published:April 2025Type:Review ArticleAuthors:Sheetal Sadguru Samant, Anvay Ashok Satpute, Mikhil Prasad Mayekar, Shamita Shamsundar Loke, Shweta Nitin Bhatkar, Mohammad Saad Golandaj, Tanvi Deepak Rawool, and Vijay Arjun Jagtap Author(s) affiliations:Sheetal Sadguru Samant*, Anvay Ashok Satpute, Mikhil Prasad Mayekar, Shamita Shamsundar Loke, Shweta Nitin Bhatkar, Mohammad Saad Golandaj, Tanvi Deepak Rawool, Vijay Arjun Jagtap Department of Pharmacognosy and Phytochemistry, Yashwantrao Bhonsale College of Pharmacy, University of Mumbai, Sawantwadi, Maharashtra, INDIA. Abstract:Sea sponges are among the oldest living creatures on Earth that have evolved complex chemical defenses to thrive in the ocean's competitive environment. These marine animals have developed an impressive array of bioactive compounds with therapeutic applications. This article explores bioactive compounds derived from sea sponges, showcasing their remarkable therapeutic potential. The article begins by introducing the fascinating world of sea sponges, highlighting their unique biology and ecology. We then delve into the various bioactive compounds isolated from sea sponges. The review highlights the anticancer properties of sea sponge-derived compounds demonstrating their potential in cancer treatment. We also explore their antimicrobial and anti-inflammatory activities, showcasing their potential in combating infectious diseases and inflammatory disorders. The article further discusses the challenges and opportunities in harnessing the bioactive potential of sea sponges. This review serves as a comprehensive resource for researchers, scientists, and students interested in marine biomedicine and natural product drug discovery. Keywords:Anti-inflammatory, anticancer, Bioactive compounds, Drug Discovery, Marine biomedicine, Sea sponges, Therapeutic potentialView:PDF (247.34 KB) PDF Thumbnails Document Outline Search Document Find Toggle Sidebar Previous Next Page: Fullscreen Print Download Current View Zoom Out Zoom In Automatic Zoom Actual Size Fit Page Full Width 50% 75% 100% 125% 150% 200% More Information Less Information Close Click here to download the PDF file. Images The Ocean's Treasure Trove: Bioactive Compounds from Sea Sponges KeywordsSea spongesBioactive compoundsTherapeutic potentialAnticancerAnti-inflammatoryMarine biomedicineDrug discovery ‹ Exploring the Male Antifertility Potential of Medicinal Plants: A Comprehensive Review up A Comprehensive Review on Medicinal Herbal Plant with Potential Hypolipidemic Activity ›