Secondary Metabolites and Bioactivities of Albizia Anthelmintica

Tahia K Mohamed; Mahmoud I Nassar; Ahmed H Gaara; Walaa A El-Kashak; Iñaki Brouard; Sayed A El-Toumy

Secondary Metabolites and Bioactivities of Albizia Anthelmintica

Articles

Abstract

Pharmacognosy Research,2013,5,2,80-85.

DOI:10.4103/0974-8490.110530

Published:April 2013

Type:Original Article

Authors:

Author(s) affiliations:

Tahia K. Mohamed¹, Mahmoud I. Nassar¹, Ahmed H. Gaara^1,2, Walaa A. El‑Kashak¹, Iñaki Brouard³, Sayed A. El‑Toumy⁴

¹Department of Chemistry of Natural Compounds, National Research Centre, Dokki 12622 Cairo, Egypt.

²Department of Chemistry, College of Science, Jazan University, Jazan, Saudi Arabia.

³Instituto De Productos Naturales Y Agrobiología, Av. Astrofisico F. Sanchez 3, 38206 La Laguna, Tenerife, Spain.

⁴Department of Chemistry of Tannins, National Research Centre, Dokki 12622 Cairo, Egypt.

Abstract:

Background: Albizia species are rich in phenolics and terpenes in the different plant organs. They are widely used in traditional Chinese medicine. So this study investigated the phytochemical and biological activities of Albizia Anthelmintica. Materials and Methods: Column chromatography has been performed for the isolation of compounds. Bioactivity studies of A. anthelmintica leaves were carried out on aqueous ethanol extract and some pure compounds were tested for their antioxidant activities. Results: Eight compounds have been isolated for the first time from A. anthelmintica. The aqueous ethanol extract of A. anthelmintica showed moderate anti-inflammatory activity and significant for both analgesic and antioxidant activities. Quercetin-3-O-β-D-glucopyranoside, kaempferol-3-O-β-D-glucopyranoside, kaempferol-3-O-(6β-O-galloyl-β-D-glucopyranoside and quercetin-3-O-(6β-O-galloyl-β-D-glucopyranoside) exhibited potent antioxidant scavenging activity towards diphenyl-picrylhydrazine.