Isolation of β-sitosterol Diglucosyl caprate from Alpinia galanga

SB Jaju; NH Indurwade; DM Sakarkar; NK Fuloria; MD Ali; SP Basu

Isolation of β-sitosterol Diglucosyl caprate from Alpinia galanga

Articles

Abstract

Pharmacognosy Research,2010,2,4,264-266.

DOI:10.4103/0974-8490.69129

Published:September 2010

Type:Original Article

Authors:

Author(s) affiliations:

SB Jaju¹, NH Indurwade¹, DM Sakarkar¹, NK Fuloria², MD Ali³, SP Basu⁴

¹S. N. Institute of Pharmacy, Pusad, Amravati University, MS - 445 204, India.

²Rameesh Institute of Vocational and Technical Education, Knowledge Park -II, Greater Noida - 201 306, UP, India.

³Department of Pharmacognosy, Jamia Hamdard, New Delhi - 110 065, India.

⁴Department of Pharmaceutical Technology, NIET, Knowledge Park -II, Greater Noida - 201 306, UP, India

Abstract:

Background: The purpose of present investigation to isolate β-sitosterol diglucosyl caprate from the rhizomes of Alpinia galanga. Methods: The methanolic extract of the rhizomes of plant Alpinia galanga was subjected to column chromatography and was eluted with ethyl acetate-methanol (99:1) to yield compound (AG5) β-sitosterol diglucosyl caprate. Various spectral techniques such as Ultraviolet (UV), Infrared (IR), Hydrogen Nuclear Magnetic Resonance (1HNMR), Carbon Nuclear Magnetic Resonance (13CNMR), and MASS spectrometry (MS), were employed to determine and elucidate. Results: Chemical and spectral investigation of extract furnished a new steroidal glycoside. Conclusion: The isolated compound β-sitosterol diglucosyl caprate could serve as a lead compound in synthesis of steroids.

Keywords:Alpinia galanga, Methanolic extract, Rhizomes, β-sitosterol diglucosyl caprate