Triterpenes from Euphorbia rigida

Noureddine Gherraf; Amar Zellagui; Naglaa S Mohamed; Taha A Hussien; Tarik A Mohamed; Mohamed-Elamir F Hegazy; Salah Rhouati; Mahmoud F M Moustafa; Magdi A El-Sayed; Abou El-Hamd H Mohamed

Triterpenes from Euphorbia rigida

Articles

Abstract

Pharmacognosy Research,2010,2,3,159-162.

DOI:10.4103/0974-8490.65510

Published:July 2010

Type:Original Article

Authors:

Author(s) affiliations:

Noureddine Gherraf¹, Amar Zellagui¹, Naglaa S Mohamed², Taha A Hussien³, Tarik A Mohamed⁴, Mohamed-Elamir F Hegazy⁵, Salah Rhouati¹, Mahmoud F. M. Moustafa⁶, Magdi A El-Sayed⁷, Abou El-Hamd H Mohamed²

¹Laboratory of Natural Products and Organic Synthesis, Department of Chemistry, Faculty of Science, University Mentouri - Constantine, Algeria

²Department of Chemistry, Aswan-Faculty of Science, South Valley University, Aswan, Egypt

³Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmacy, Applied Sciences University, Amman, Jordan - 119 31, Jordan

⁴Department of Pharmacognosy, Faculty of Pharmacy, El-Minia University, El-Minia - 615 19, Egypt

⁵Chemistry of Medicinal Plant Department, National Research Centre, Dokki, Giza - 126 22, Egypt

⁶Department of Biological Sciences, College of Science, King Khalid University, 61413, Saudi Arabia

⁷Department of Botany, Aswan-Faculty of Science, South Valley University, Aswan, Egypt

Abstract:

Phytochemical studies of the aerial parts of Euphorbia rigida afforded three triterpenes: betulin (1), cycloart-23Z-ene-3, 25-diol (2) and cycloartan-3, 24, 25-triol (3), firstly isolated from this plant. The structures and relative stereochemistry were determined on the basis of extensive spectroscopic analyses, including 1D and 2D NMR experiments (1H NMR, 13C NMR, COSY, NOESY, HMQC and HMBC).

Keywords:Cycloartan triterpene, Euphorbia rigida, Euphorbiaceae