Biological activity of Crambe orientalis L. growing in Iran

Articles

Abstract
Pharmacognosy Research,2009,1,3,125-129.
DOI:
Published:January 2010
Type:Original Article
Authors:
Author(s) affiliations:

SM Razavi1, G Zarrini2, S Zahri1, K Ghasemi1, S Mohammadi1

1Department of Biology, University of Mohaghegh Ardabili, Ardabil, IRAN.

2Depatrment of Animal Sciences, Faculty of Natural Sciences, University of Tabriz, Tabriz, IRAN.

Abstract:

Crambe orientalis (Brassicaceae) is a perennial herb growing wild in Iran. Cytotoxic, antioxidant, antimicrobial and phytotoxic effects of the plant leaves extracts have been evaluated by MTT, DPPH, Disc diffusion and lettuce assays, respectively. Our results showed that dichloromethane and methanol extracts of the plant leaves exhibited high cytotoxic effects against Mc-Coy cell line with IC50 value of 659 and 432 -g/ml, respectively. The extracts indicated high antioxidant activity with RC50 value of 33.3 and 40.5 -g/ml, respectively. Methanol extract showed strong antibacterial activity against both gram-positive and gram-negative bacteria. All the extracts displayed significant allelopatic potential, as well as. It is assumed that biological activity of the plant may be related to presence of isothiocyanates in the plant leaves.

PDF
Current View
Click here to download the PDF file.
Images

Biological activity of Crambe orientalis L. growing in Iran

Keywords

Cite This Article